An operational definition of epigenetics

Shelley L. Berger; Tony Kouzarides; Ramin Shiekhattar; Ali Shilatifard

doi:10.1101/gad.1787609

An operational definition of epigenetics

Shelley L. Berger, Tony Kouzarides, Ramin Shiekhattar, Ali Shilatifard

Biochemistry and Molecular Genetics

Research output: Contribution to journal › Article › peer-review

1049 Scopus citations

Abstract

A recent meeting (December 2008) regarding chromatinbased epigenetics was hosted by the Banbury Conference Center and Cold Spring Harbor Laboratory. The intent was to discuss aspects of epigenetic control of genomic function, and to arrive at a consensus definition of "epigenetics" to be considered by the broader community. It was evident that multiple mechanistic steps lead to the stable heritance of the epigenetic phenotype. Below we provide our view and interpretation of the proceedings at the meeting.

Original language	English (US)
Pages (from-to)	781-783
Number of pages	3
Journal	Genes and Development
Volume	23
Issue number	7
DOIs	https://doi.org/10.1101/gad.1787609
State	Published - Apr 1 2009

Keywords

DNA methylation
Histone modification
Histone variant
Noncoding RNA

ASJC Scopus subject areas

Genetics
Developmental Biology

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An operational definition of epigenetics

Abstract

Keywords

ASJC Scopus subject areas

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