An Optimal Sliding Choke Antenna for Hepatic Microwave Ablation

Punit Prakash*, Mark C. Converse, John G. Webster, David M. Mahvi

*Corresponding author for this work

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

Microwave ablation (MWA) is a minimally invasive technique increasingly used for thermal therapy of liver tumors. Effective MWA requires efficient interstitial antennas that destroy tumors and a margin of healthy tissue, in situ, while minimizing damage to the rest of the organ. Previously, we presented a method for optimizing MWA antenna designs by coupling finite element method models of antennas with a real-coded, multiobjective genetic algorithm. We utilized this procedure to optimize the design of a minimally invasive choke antenna that can be used to create near-spherical ablation zones of adjustable size (radius 1–2 cm) by adjusting treatment durations and a sliding structure of the antenna. Computational results were validated with experiments in ex vivo bovine liver. The optimization procedure yielded antennas with reflection coefficients below −30 dB, which were capable of creating spherical ablation zones up to 2 cm in radius using 100 W input power at 2.45 GHz with treatment durations under 2 min.

Original languageEnglish (US)
Pages (from-to)2470-2476
Number of pages7
JournalIEEE Transactions on Biomedical Engineering
Volume56
Issue number10
DOIs
StatePublished - Oct 2009

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Keywords

  • Ablation
  • algorithms (GAs)
  • finite element methods (FEMs)
  • genetic
  • microwave antennas

ASJC Scopus subject areas

  • Biomedical Engineering

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