An ultra-thin PDMS membrane as a bio/micro-nano interface: Fabrication and characterization

Abel L. Thangawng; Rodney S. Ruoff; Melody A. Swartz; Matthew R. Glucksberg

doi:10.1007/s10544-007-9070-6

An ultra-thin PDMS membrane as a bio/micro-nano interface: Fabrication and characterization

Abel L. Thangawng, Rodney S. Ruoff, Melody A. Swartz, Matthew R. Glucksberg^*

^*Corresponding author for this work

Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

173 Scopus citations

Abstract

We report a method for making ultra-thin PDMS membrane devices. Freely suspended membranes as thin as 70 nm have been fabricated. Bulging tests were performed with a custom built fluidic cell to characterize large circular membranes. The fluidic cell allows the media (such as air or water) to wet one side of the membrane while maintaining the other side dry. Pressure was applied to the membrane via a liquid manometer through the fluidic cell. The resulting load-deflection curves show membranes that are extremely flexible, and they can be reproducibly loaded and unloaded. Such devices may potentially be used as mechanical and chemical sensors, and as a bio-nano/micro interface to study cellular mechanics in both static and dynamic environments.

Original language	English (US)
Pages (from-to)	587-595
Number of pages	9
Journal	Biomedical Microdevices
Volume	9
Issue number	4
DOIs	https://doi.org/10.1007/s10544-007-9070-6
State	Published - Aug 2007

Funding

Acknowledgement Funding for this project was provided by NIH (HL075217) and NSF (BES-0134551).

Keywords

Bulging test
Microfabrication
PDMS membrane
Ultra sensitive membrane

ASJC Scopus subject areas

Biomedical Engineering
Molecular Biology

Access to Document

10.1007/s10544-007-9070-6

Cite this

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title = "An ultra-thin PDMS membrane as a bio/micro-nano interface: Fabrication and characterization",

abstract = "We report a method for making ultra-thin PDMS membrane devices. Freely suspended membranes as thin as 70 nm have been fabricated. Bulging tests were performed with a custom built fluidic cell to characterize large circular membranes. The fluidic cell allows the media (such as air or water) to wet one side of the membrane while maintaining the other side dry. Pressure was applied to the membrane via a liquid manometer through the fluidic cell. The resulting load-deflection curves show membranes that are extremely flexible, and they can be reproducibly loaded and unloaded. Such devices may potentially be used as mechanical and chemical sensors, and as a bio-nano/micro interface to study cellular mechanics in both static and dynamic environments.",

keywords = "Bulging test, Microfabrication, PDMS membrane, Ultra sensitive membrane",

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note = "Funding Information: Acknowledgement Funding for this project was provided by NIH (HL075217) and NSF (BES-0134551).",

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AU - Swartz, Melody A.

AU - Glucksberg, Matthew R.

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AB - We report a method for making ultra-thin PDMS membrane devices. Freely suspended membranes as thin as 70 nm have been fabricated. Bulging tests were performed with a custom built fluidic cell to characterize large circular membranes. The fluidic cell allows the media (such as air or water) to wet one side of the membrane while maintaining the other side dry. Pressure was applied to the membrane via a liquid manometer through the fluidic cell. The resulting load-deflection curves show membranes that are extremely flexible, and they can be reproducibly loaded and unloaded. Such devices may potentially be used as mechanical and chemical sensors, and as a bio-nano/micro interface to study cellular mechanics in both static and dynamic environments.

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An ultra-thin PDMS membrane as a bio/micro-nano interface: Fabrication and characterization

Abstract

Funding

Keywords

ASJC Scopus subject areas

Access to Document

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