An update on mechanical circulatory support for heart failure therapy

Hadi Daood Toeg, Talal Al-Atassi, Jose Perez Garcia, Marc Ruel*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


PURPOSE OF REVIEW: This article aims to review contemporary studies that utilized mechanical circulatory support (MCS) in the treatment of heart failure and to elaborate on prospective mechanical alternatives. RECENT FINDINGS: There is a growing need for a well-tolerated, durable and effective MCS option in patients with refractory heart failure. In previous years, the primary indication for MCS therapy supported bridge to transplantation. These early left ventricular assist devices (LVADs) suffered significant adverse events, thereby limiting their prolonged use. With the introduction of newer continuous flow LVADs, with lower morbidity, neurological events, pump failure and the expanded indication use (i.e. destination therapy), the overall number of implanted patients has grown. SUMMARY: There has been a dramatic advancement of durability found in the second and third-generation, continuous flow LVADs, along with improved survival rates in patients receiving these devices for destination therapy. MCS may soon become the treatment option of choice in refractory heart failure patients, especially with further evolution of less invasive approaches, smaller designs, and energy sources.

Original languageEnglish (US)
Pages (from-to)167-173
Number of pages7
JournalCurrent opinion in cardiology
Issue number2
StatePublished - Mar 1 2014


  • Cardiac surgery
  • Heart failure
  • Left ventricular assist device

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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