An update on the systemic therapy of malignant salivary gland cancers: Role of chemotherapy and molecular targeted agents

Keyphrases

• Chemotherapy 100%
• Systemic Therapy 100%
• Molecular Targeted Agents 100%
• Salivary Gland Cancer 100%
• Human Epidermal Growth Factor Receptor 2 (HER2) 66%
• Response Rate 66%
• Duration of Response 66%
• Salivary Gland Malignancy 66%
• Vascular Endothelial Growth Factor 33%
• Well-defined 33%
• Overexpression 33%
• Tumor 33%
• Molecular Markers 33%
• Putative Drug Targets 33%
• Poor Prognosis 33%
• Metastatic Disease 33%
• Head-and-neck Cancer 33%
• Oncoprotein 33%
• Conventional Chemotherapy 33%
• All Cancer 33%
• Recurrent Disease 33%
• Initial Management 33%
• Acinar Cells 33%
• Poor Clinical Outcomes 33%
• ErbB2 33%
• Aggressiveness 33%
• Small Sample Size 33%
• Prognostic Significance 33%
• P53 Protein 33%
• Molecular Targeted Therapy 33%
• Investigational Drugs 33%
• Distinct Subtypes 33%
• Clinical Behavior 33%
• Adjuvant Radiation Therapy 33%
• Adenocarcinoma 33%
• Single-agent Chemotherapy 33%
• Objective Response Rate 33%
• Suboptimal Response 33%
• Combination Chemotherapy 33%
• Cytotoxic Agents 33%
• ErbB1 33%
• Head-and-neck Region 33%
• Resectability 33%
• Rare Malignancy 33%
• Established Drugs 33%
• Salivary Gland Tumor 33%
• New Indication 33%
• Mutated p53 33%
• Locoregional Recurrence 33%
• Epidermal Growth Factor Receptor Family 33%
• EGFR Overexpression 33%
• Salivary Duct 33%
• Adenoid Cystic 33%
• Mucoepidermoid 33%

Medicine and Dentistry

• Systemic Therapy 100%
• Salivary Gland Cancer 100%
• Cancer 100%
• Epidermal Growth Factor Receptor 80%
• Salivary Gland 40%
• Neoplasm 20%
• Recurrent Disease 20%
• Receptor Family 20%
• Metastatic Carcinoma 20%
• Adenocarcinoma 20%
• Vasculotropin 20%
• Protein P53 20%
• Prognostication 20%
• Epidermal Growth Factor Receptor 2 20%
• Combination Chemotherapy 20%
• Molecularly Targeted Therapy 20%
• Salivary Gland Neoplasm 20%
• Investigational Drug 20%
• Neck 20%
• Parotid Duct 20%
• Diseases 20%
• Radiation Therapy 20%
• Molecular Marker 20%
• Cytotoxic Agent 20%