An Update on Vitrectomy Surgery and Retinal Detachment Repair in Sickle Cell Disease

Lee M. Jampol, James L. Green, Morton F. Goldberg, Gholam A. Peyman

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


Eighteen patients (19 eyes) with sickling hemoglobinopathies underwent vitrectomy or scleral buckling operations. The indications for surgery were tractional or rhegmatogenous retinal detachment or vitreous hemorrhage. The retina was reattached in all four patients with rhegmatogenous detachments requiring scleral buckling surgery but no vitrectomy. All had excellent visual acuity postoperatively. Four of the five patients with vitreous hemorrhage requiring vitrectomy without buckling had substantial improvement in visual acuity. In ten patients with vitreous hemorrhage with either preexisting or iatrogenic retinal breaks, rhegmatogenous detachment, or tractional detachment, the rate of improvement in visual acuity was only 50%. Problems associated with vitreous or retinal surgery in patients with sickling hemoglobinopathies include iatrogenic retinal breaks, intraocular bleeding and secondary glaucoma, anterior segment ischemia, and systemic sickling.

Original languageEnglish (US)
Pages (from-to)591-593
Number of pages3
JournalArchives of ophthalmology
Issue number4
StatePublished - Apr 1982

ASJC Scopus subject areas

  • Ophthalmology


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