@inbook{3534ee7d75fb4d8f9ec52c9744a7accf,
title = "Analyses of the dynamic properties of nuclear lamins by fluorescence recovery after photobleaching (FRAP) and fluorescence correlation spectroscopy (FCS)",
abstract = "The major structural components of the nuclear lamina are the A- and B-type nuclear lamin proteins which are also present in the nucleoplasm. Studies of molecular movements of the lamins in both the lamina and nucleoplasm of living cell nuclei have provided insights into their roles in maintaining nuclear architecture. In this chapter, we present protocols for quantitatively measuring the mobilities of lamin proteins by fluorescence recovery after photobleaching (FRAP) and fluorescence correlation spectroscopy (FCS) in mammalian cell nuclei.",
keywords = "FCS, FRAP, Lamin, Lamina",
author = "Shimi Takeshi and Pack, {Chan Gi} and Goldman, {Robert D.}",
note = "Funding Information: This work was supported by grants from the National Institutes of Health (GM106023) and (CA03176) Award to R.D.G. Publisher Copyright: {\textcopyright} Springer Science+Business Media New York 2016.",
year = "2016",
doi = "10.1007/978-1-4939-3530-7_5",
language = "English (US)",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "99--111",
booktitle = "Methods in Molecular Biology",
}