Analysis of computer alerts suggesting oral medication use during computerized order entry of i.v. medications

William Galanter*, Xiaoqing Liu, Bruce L. Lambert

*Corresponding author for this work

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Purpose. Compliance with computer alerts suggesting oral medication use during computerized order entry of i.v. medications was analyzed. Summary. Using automated computerized clinical decision support (CDS) to suggest converting i.v. medications to oral alternatives can reduce medication costs for hospitalized patients, but prescriber noncompliance limits the effectiveness of such interventions. Clearer understanding of the factors associated with noncompliance to alerts may facilitate the design of more effective CDS systems. Electronic medical record data were retrospectively analyzed to measure the rate of compliance with a CDS alert that suggested converting to an equivalent oral form of a drug at the time of ordering the i.v. formulation. Multiple logistic regression was used to examine the associations among medication type, clinician characteristics, hospital service type, time of order, and compliance with the i.v.-to-oral conversion recommendation. The main outcome was compliance with the alert, measured at the level of the individual medication order. The mean ± S.E. overall compliance rate was 18.7% ± 0.6%. Compliance varied among the medications, with methylprednisolone having the lowest (8%) and famotidine the highest (32%) (p < 0.05). Nurses had the highest compliance rate (35%) while pharmacists had the lowest (10%) (p < 0.05). Medical house staff (19%) and medical faculty (21%) complied at similar rates. The intensive care units had lower compliance rates than did the medical-surgical ward (15% versus 21%, p < 0.05). Conclusion. CDS alerts to convert 12 i.v. medications to oral alternatives were developed and implemented in an urban tertiary hospital. Compliance rates for the alerts were relatively low and varied by medication, location, and clinician type.

Original languageEnglish (US)
Pages (from-to)1101-1105
Number of pages5
JournalAmerican Journal of Health-System Pharmacy
Volume67
Issue number13
DOIs
StatePublished - Jul 1 2010

Keywords

  • Compliance
  • Computers
  • Costs
  • Decision making
  • Drug administration route
  • Health professions
  • Hospitals
  • Medication orders

ASJC Scopus subject areas

  • Pharmacology
  • Health Policy

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