Analysis of neuropsychological functioning in patients with chronic fatigue syndrome

Jordan Grafinan*, Vicki Schwartz, Janet K. Dale, Marten Scheffers, Christine Houser, Stephen E. Straus

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

108 Scopus citations


Memory impairment dominates the cognitive complaints of patients with chronic fatigue syndrome (CFS). Twenty CFS patients were available for studies with a clinical and experimental battery composed of memory and cognitive tests. The results on objective testing indicated that the CFS patients had some mild memory Impairment, but only on tasks requiring conceptually driven encoding and retrieval processes. There were no associations between the nature of the precipitating illness, self ratings of fatigue, physical findings, or laboratory determination and objective memory performance or self report of memory functioning. These generally negative results indicate that memory impairment in CFS patients is typically mild and involves memory processes that participate in conceptualising information.

Original languageEnglish (US)
Pages (from-to)684-689
Number of pages6
JournalJournal of Neurology, Neurosurgery and Psychiatry
Issue number6
StatePublished - 1993

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Surgery


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