TY - GEN
T1 - Analysis of the intended and actual orientations of directional deep brain stimulation leads across deep brain stimulation systems
AU - Henry, Kaylee R.
AU - Miulli, Milina M.
AU - Elahi, Behzad
AU - Rosenow, Joshua
AU - Nolt, Mark
AU - Golestanirad, Laleh
N1 - Funding Information:
* Research supported by the NIH Grant R01EB030324. K.R. Henry is with the Department of Biomedical Engineering, Northwestern University, Evanston, IL 60608 USA. M.M. Miulli is with the Department of Neuroscience and Department of Global Health Studies, Northwestern University, Evanston, IL 60608 USA. B. Elahi is with the Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL 60611 USA.
Publisher Copyright:
© 2022 IEEE.
PY - 2022
Y1 - 2022
N2 - Deep brain stimulation (DBS) offers therapeutic benefits to patients suffering from a variety of treatment-resistant neurological and psychiatric disorders. The newest generation of DBS devices now offer directional leads, which utilize segmented electrodes to direct current asymmetrically to the neuronal tissue. Since segmented electrodes offer a larger degree of freedom for contact positioning, it is critical to assess how well the surgically intended and the actual orientation of the lead match to facilitate programming and allow appropriate interpretation of the therapeutic outcome. Postoperative image analysis algorithms, such as DiODe, are commonly used to determine DBS leads' actual orientation. In this work, we used DiODe to compare the deviation between intended and actual orientations of DBS leads across two most commonly implanted directional DBS systems, namely, Boston Scientific Cartesia™ and St. Jude Medical Infinity. This study is the first to investigate the rotation of leads from both DBS systems in a large group of 86 patients. Clinical Relevance- Our results quantify the variability between the surgically intended and actual orientations of Boston Scientific Vercise and St. Jude Medical Infinity DBS systems thus highlighting the need to develop more precise implantation procedures.
AB - Deep brain stimulation (DBS) offers therapeutic benefits to patients suffering from a variety of treatment-resistant neurological and psychiatric disorders. The newest generation of DBS devices now offer directional leads, which utilize segmented electrodes to direct current asymmetrically to the neuronal tissue. Since segmented electrodes offer a larger degree of freedom for contact positioning, it is critical to assess how well the surgically intended and the actual orientation of the lead match to facilitate programming and allow appropriate interpretation of the therapeutic outcome. Postoperative image analysis algorithms, such as DiODe, are commonly used to determine DBS leads' actual orientation. In this work, we used DiODe to compare the deviation between intended and actual orientations of DBS leads across two most commonly implanted directional DBS systems, namely, Boston Scientific Cartesia™ and St. Jude Medical Infinity. This study is the first to investigate the rotation of leads from both DBS systems in a large group of 86 patients. Clinical Relevance- Our results quantify the variability between the surgically intended and actual orientations of Boston Scientific Vercise and St. Jude Medical Infinity DBS systems thus highlighting the need to develop more precise implantation procedures.
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U2 - 10.1109/EMBC48229.2022.9871608
DO - 10.1109/EMBC48229.2022.9871608
M3 - Conference contribution
C2 - 36086443
AN - SCOPUS:85138126693
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 1725
EP - 1728
BT - 44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2022
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2022
Y2 - 11 July 2022 through 15 July 2022
ER -