Analysis of the intended and actual orientations of directional deep brain stimulation leads across deep brain stimulation systems

Kaylee R. Henry, Milina M. Miulli, Behzad Elahi, Joshua Rosenow, Mark Nolt, Laleh Golestanirad*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Deep brain stimulation (DBS) offers therapeutic benefits to patients suffering from a variety of treatment-resistant neurological and psychiatric disorders. The newest generation of DBS devices now offer directional leads, which utilize segmented electrodes to direct current asymmetrically to the neuronal tissue. Since segmented electrodes offer a larger degree of freedom for contact positioning, it is critical to assess how well the surgically intended and the actual orientation of the lead match to facilitate programming and allow appropriate interpretation of the therapeutic outcome. Postoperative image analysis algorithms, such as DiODe, are commonly used to determine DBS leads' actual orientation. In this work, we used DiODe to compare the deviation between intended and actual orientations of DBS leads across two most commonly implanted directional DBS systems, namely, Boston Scientific Cartesia™ and St. Jude Medical Infinity. This study is the first to investigate the rotation of leads from both DBS systems in a large group of 86 patients. Clinical Relevance- Our results quantify the variability between the surgically intended and actual orientations of Boston Scientific Vercise and St. Jude Medical Infinity DBS systems thus highlighting the need to develop more precise implantation procedures.

Original languageEnglish (US)
Title of host publication44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2022
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1725-1728
Number of pages4
ISBN (Electronic)9781728127828
DOIs
StatePublished - 2022
Event44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2022 - Glasgow, United Kingdom
Duration: Jul 11 2022Jul 15 2022

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Volume2022-July
ISSN (Print)1557-170X

Conference

Conference44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2022
Country/TerritoryUnited Kingdom
CityGlasgow
Period7/11/227/15/22

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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