TY - JOUR
T1 - Achados anatômicos e neuropsicológicos de idosos cognitivamente saudáveis com baixa escolaridade em uma coorte brasileira
AU - Foss, Maria Paula
AU - Beserra Diniz, Paula Rejane
AU - da Roza, Daiane Leite
AU - Gefen, Tamar
AU - Maher, Amanda Cook
AU - Formigheri, Paulo
AU - Spedo, Carina T.
AU - Garrido Salmon, Carlos Ernesto
AU - Tumas, Vitor
AU - Speciali, José Geraldo
AU - Santos, Antônio Carlos
N1 - Funding Information:
Tamar Gefen, PhD is supported by grants from the National Institute on Aging (T32 AG20506) and the Florane and Jerome Rosenstone Fellowship. Daiane Leite da Roza, PhD is supported by grant from FAPESP (process n? 2018/07581-2).
Publisher Copyright:
© 2019, Academia Brasileira de Neurologia. All rights reserved.
PY - 2019/10/1
Y1 - 2019/10/1
N2 - In elderly individuals, low educational level may represent a risk factor for the development of dementia and a proxy of cognitive reserve. Objective: This study examined the cognitive and neuroanatomic correlates of high versus low educational levels in cognitively healthy community-dwelling older adults in Brazil. Methods: Fifty-three older adults (mean age: 68±5.3 years) were divided into a “low education” group [LE; 1-4 years of education (N=33)] and “high education” group [HE; >11 years of education (N=20)]. Both groups completed a comprehensive neuropsychological battery and underwent in vivo structural MRI close to the time of testing. Results: Higher educational level increased the chance of having better scores on neuropsychological tests, including verbal and visual delayed recall of information, verbal learning, category fluency, global cognition, and vocabulary. Better scores on these tests were observed in the HE group relative to the LE group. Despite this, there were no group differences between MRI measures. Conclusion: Older adults with higher educational levels showed better scores on neuropsychological measures of cognition, highlighting the need for education-adjusted norms in developing countries. Given the absence of differences in structural anatomy between the groups, these findings appear to be best explained by theories of cognitive reserve.
AB - In elderly individuals, low educational level may represent a risk factor for the development of dementia and a proxy of cognitive reserve. Objective: This study examined the cognitive and neuroanatomic correlates of high versus low educational levels in cognitively healthy community-dwelling older adults in Brazil. Methods: Fifty-three older adults (mean age: 68±5.3 years) were divided into a “low education” group [LE; 1-4 years of education (N=33)] and “high education” group [HE; >11 years of education (N=20)]. Both groups completed a comprehensive neuropsychological battery and underwent in vivo structural MRI close to the time of testing. Results: Higher educational level increased the chance of having better scores on neuropsychological tests, including verbal and visual delayed recall of information, verbal learning, category fluency, global cognition, and vocabulary. Better scores on these tests were observed in the HE group relative to the LE group. Despite this, there were no group differences between MRI measures. Conclusion: Older adults with higher educational levels showed better scores on neuropsychological measures of cognition, highlighting the need for education-adjusted norms in developing countries. Given the absence of differences in structural anatomy between the groups, these findings appear to be best explained by theories of cognitive reserve.
KW - Cognitive aging
KW - Cognitive reserve
KW - Educational levels
KW - MRI
KW - Neuropsychological assessment
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U2 - 10.1590/1980-57642018dn13-040003
DO - 10.1590/1980-57642018dn13-040003
M3 - Article
C2 - 31844490
AN - SCOPUS:85075920837
VL - 13
SP - 378
EP - 386
JO - Dementia e Neuropsychologia
JF - Dementia e Neuropsychologia
SN - 1980-5764
IS - 4
ER -