Androgens and menopause

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations

Abstract

The cessation of ovarian sex steroidigenesis, either as result as surgical extirpation, certain medical therapies or the gradual cessation of ovarian function, leads to menopause with all its associated physiological, physical and lifestyle changes. The changing hormonal milieu of menopause is most commonly associated with declining levels of estrogens. However, ovarian senescence also results in declining levels of androgens. Indeed, it is the loss of physiological levels of estrogens and androgens that result in the varied signs and symptoms of menopause including vasomotor symptoms, bone mineral density loss, reduced interest in sex, alterations in mood and energy and hair loss, among others. This paper will provide a review of the role of androgens in the menopause and assess the potential of androgen therapies in the management of the menopause.

Original languageEnglish (US)
Pages (from-to)491-497
Number of pages7
JournalMinerva Ginecologica
Volume61
Issue number6
StatePublished - Dec 1 2009

Keywords

  • Androgens
  • Menopause
  • Therapeutics

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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