Anesthetic management of a pediatric patient with neuroleptic malignant syndrome

Tarun Bhalla*, Joseph D. Tobias, Douglas Maxey, Amod Sawardekar

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Neuroleptic malignant syndrome (NMS) is a rare disorder which is clinically similar to malignant hyperthermia (MH). It is characterized by hyperthermia, autonomic instability, muscle rigidity, coma, rhabdomyolysis, and acidosis. Without immediate and appropriate therapy, mortality may result. NMS is associated with administration of antipsychotic medications, anti-emetic medications, and changes in the dosage of anti-parkinsonian drugs. As several similarities exist between NMS and MH, differentiating between them can be a challenge for the clinician. We report anesthetic care during magnetic resonance imaging of the brain of a 14-year-old female with bipolar and schizoaffective disorders and the recent onset of NMS.

Original languageEnglish (US)
Pages (from-to)250-253
Number of pages4
JournalJournal of Anesthesia
Issue number2
StatePublished - Apr 2012


  • Anti-psychotic medications
  • Neuroleptic malignant syndrome
  • Pediatric anesthesia

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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