TY - JOUR
T1 - Anesthetic management of a pediatric patient with neuroleptic malignant syndrome
AU - Bhalla, Tarun
AU - Tobias, Joseph D.
AU - Maxey, Douglas
AU - Sawardekar, Amod
PY - 2012/4
Y1 - 2012/4
N2 - Neuroleptic malignant syndrome (NMS) is a rare disorder which is clinically similar to malignant hyperthermia (MH). It is characterized by hyperthermia, autonomic instability, muscle rigidity, coma, rhabdomyolysis, and acidosis. Without immediate and appropriate therapy, mortality may result. NMS is associated with administration of antipsychotic medications, anti-emetic medications, and changes in the dosage of anti-parkinsonian drugs. As several similarities exist between NMS and MH, differentiating between them can be a challenge for the clinician. We report anesthetic care during magnetic resonance imaging of the brain of a 14-year-old female with bipolar and schizoaffective disorders and the recent onset of NMS.
AB - Neuroleptic malignant syndrome (NMS) is a rare disorder which is clinically similar to malignant hyperthermia (MH). It is characterized by hyperthermia, autonomic instability, muscle rigidity, coma, rhabdomyolysis, and acidosis. Without immediate and appropriate therapy, mortality may result. NMS is associated with administration of antipsychotic medications, anti-emetic medications, and changes in the dosage of anti-parkinsonian drugs. As several similarities exist between NMS and MH, differentiating between them can be a challenge for the clinician. We report anesthetic care during magnetic resonance imaging of the brain of a 14-year-old female with bipolar and schizoaffective disorders and the recent onset of NMS.
KW - Anti-psychotic medications
KW - Neuroleptic malignant syndrome
KW - Pediatric anesthesia
UR - http://www.scopus.com/inward/record.url?scp=84863202515&partnerID=8YFLogxK
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U2 - 10.1007/s00540-011-1269-2
DO - 10.1007/s00540-011-1269-2
M3 - Review article
C2 - 22101771
AN - SCOPUS:84863202515
VL - 26
SP - 250
EP - 253
JO - Journal of Anesthesia
JF - Journal of Anesthesia
SN - 0913-8668
IS - 2
ER -