Antenatal corticosteroids: Extending the practice for late-preterm and scheduled early-term deliveries?

Zeyar T. Htun*, Jacqueline C. Hairston, Cynthia Gyamfi-Bannerman, Jaime Marasch, Ana Paula Duarte Ribeiro

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Respiratory distress in late-preterm and early term infants generally may warrant admission to a special care nursery or an intensive care unit. In particular, respiratory distress syndrome and transient tachypnea of the newborn are the two most common respiratory morbidities. Antenatal corticosteroids (ACS) facilitate surfactant production and lung fluid resorption. The use of ACS has been proven to be beneficial for preterm infants delivered at less than 34 weeks’ gestation. Literature suggests that the benefits of giving antenatal corticosteroids may extend to late-preterm and early term infants as well. This review discusses the short-term benefits of ACS administration in reducing respiratory morbidities, in addition to potential long term adverse effects. An update on the current practices of ACS use in pregnancies greater than 34 weeks’ gestation and considerations of possibly extending versus restricting this practice to certain settings will also be provided.

Original languageEnglish (US)
Article number272
Issue number4
StatePublished - Apr 2021


  • Antenatal corticosteroids
  • Caesarean delivery
  • Early term
  • Late-preterm
  • RDS

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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