Kidneys from an Rh-negative cadaver donor were transplanted to two Rh-positive patients. The donor’s serum contained anti-Rho(D). In both patients, anti-Rho(D) was detected in their serum and on their red cells 3.5 -weeks after transplantation. One patient had hemolysix. The antibodies persisted for nearly six months, despite graft rejection and nephrectomy in one case. These antibodies presumably arose from passenger B lymphocytes in the grafts from the Rh-immunized donor.
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