Antibiotic considerations in the treatment of multidrug-resistant (MDR) pathogens: A case-based review

Pavani Reddy*, Smitha Chadaga, Gary A. Noskin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

The recent rise in antimicrobial resistance among health-care associated pathogens is a growing public health concern. According to the National Nosocomial Infections Surveillance System, rates of methicillin-resistant Staphylococcus aureus (MRSA) in intensive care units have nearly doubled over the last decade. Of equal importance, gram-negative agents such as Pseudomonas aeruginosa, Acinetobacter baumannii, and extended-spectrum beta lactamase-producing Enterobacteriaceae demonstrate increasing resistance to third-generation cephalosporins, fluoroquinolones, and, in some cases, carbapenems. As a consequence, hospitalists may find themselves utilizing new antibiotics in the treatment of bacterial infections. This case-based review will highlight 8 antibiotics that have emerging clinical indications in treating these multidrug-resistant (MDR) pathogens.

Original languageEnglish (US)
Pages (from-to)E8-E15
JournalJournal of hospital medicine
Volume4
Issue number6
DOIs
StatePublished - Jul 1 2009

Keywords

  • Colistin
  • Dalbavancin
  • Daptomycin
  • Doripenem
  • Ertapenem
  • Linezolid
  • Multidrug-resistant
  • Quinupristin-dalfopristin
  • Tigecycline

ASJC Scopus subject areas

  • Leadership and Management
  • Internal Medicine
  • Fundamentals and skills
  • Health Policy
  • Care Planning
  • Assessment and Diagnosis

Fingerprint Dive into the research topics of 'Antibiotic considerations in the treatment of multidrug-resistant (MDR) pathogens: A case-based review'. Together they form a unique fingerprint.

Cite this