Antibiotic Resistance in Neonatal Intensive Care Unit Pathogens: Mechanisms, Clinical Impact, and Prevention Including Antibiotic Stewardship

Sameer J. Patel, Lisa Saiman*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

68 Scopus citations

Abstract

Antimicrobial-resistant pathogens are of increasing concern in the neonatal intensive care unit population. A myriad of resistance mechanisms exist in microorganisms, and management can be complex because broad-spectrum antibiotics are increasingly needed. Control and prevention of antibiotic-resistant organisms (AROs) require an interdisciplinary team with continual surveillance. Judicious use of antibiotics; minimizing exposure to risk factors, when feasible; and effective hand hygiene are crucial interventions to reduce infection and transmission of AROs.

Original languageEnglish (US)
Pages (from-to)547-563
Number of pages17
JournalClinics in Perinatology
Volume37
Issue number3
DOIs
StatePublished - Sep 2010

Keywords

  • Antibiotic resistance
  • Antibiotic stewardship
  • Infection control
  • Neonatal intensive care unit
  • Prevention

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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