Antibodies, boosters, and optimizing SARS-CoV-2 vaccines for transplantation: A call for more research

Michael G. Ison*, Emily Blumberg, Natasha Halasa, Dan Kaul, Nicole M. Theodoropoulos, Cameron R. Wolfe

*Corresponding author for this work

Research output: Contribution to journalComment/debatepeer-review

2 Scopus citations

Abstract

Despite emerging data suggesting reduced antibody responses among solid organ transplant recipients following SARS-CoV-2 vaccine, critical unanswered questions remain. The clinical implications of the reduced humoral response need to be assessed through prospective studies. Studies are likewise needed to inform which vaccine dosing strategies result in improved immunity and if such approaches maximize protection against severe infection in the vulnerable transplant population.

Original languageEnglish (US)
JournalAmerican Journal of Transplantation
DOIs
StateAccepted/In press - 2021

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation
  • Pharmacology (medical)

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