Antibodies in the treatment of human cancer

T. M. Kuzel*, S. T. Rosen

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations

Abstract

Monoclonal antibody-based therapy has the theoretic appeal of selective targeting of tumor cells. Most promising is the use of toxins and radioisotope immunoconjugates in the treatment of hematologic malignancies. Obstacles to effective treatment have been defined and solutions are being pursued. The future use of this therapeutic strategy will be determined by creative approaches to enhance delivery, decrease immunogenicity, and maximize potency of antibody reagents.

Original languageEnglish (US)
Pages (from-to)622-626
Number of pages5
JournalCurrent opinion in oncology
Volume6
Issue number6
DOIs
StatePublished - Jan 1 1994

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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