Antibody-dependent and spontaneous lympholysis in urologic cancer patients

T. L. Katliff, K. E. McCool, W. J. Catalona*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

To evaluate cytotoxic function mediated by killer lymphocytes and macrophages in urological cancer patients, we examined antibody-dependent and spontaneous lympholysis of chicken erythrocyte target cells, which is mediated by macrophages. Our results demonstrate a discordance between cytotoxic mechanisms in cancer patients, killer-cell function being impaired whilst macrophage-mediated cytotoxicity was increased.

Original languageEnglish (US)
Pages (from-to)667-675
Number of pages9
JournalBritish Journal of Cancer
Volume39
Issue number6
DOIs
StatePublished - Jun 1979

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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