Antidepressant medication use during breastfeeding

Teresa Lanza Di Scalea, Katherine L. Wisner

Research output: Contribution to journalArticlepeer-review

71 Scopus citations

Abstract

We performed an electronic search by using MEDLINE, PreMEDLINE, Current Contents, Biological Abstracts, and PsycINFO from June 2002 to December 2008 using the following terms: "antidepressant drugs", "antidepressive agents", "human milk", "lactation" , and "breastfeeding" and the generic name of each antidepressant. Articles in the English language with reports of antidepressants in maternal serum or breast milk, infant serum, and short-term and long-term clinical outcomes in the infants were obtained. The search yielded a total of 31 empirical papers. Breastfeeding and antidepressant treatments are not mutually exclusive. Sertraline, paroxetine, nortriptyline, and imipramine are the most evidence-based medications for use during breastfeeding.

Original languageEnglish (US)
Pages (from-to)483-497
Number of pages15
JournalClinical Obstetrics and Gynecology
Volume52
Issue number3
DOIs
StatePublished - Sep 2009

Keywords

  • Antidepressant
  • Breastfeeding
  • Nursing infant

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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