Antigonadal Effect of Melatonin in Pinealectomized and Intact Male Hamsters

Fred W. Turek*

*Corresponding author for this work

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

The administration of mela-tonin (12-150 μg/day) via subcutaneous Si-lastic capsules inhibited photic-induced testicular recrudescence to the same degree in both pinealectomized and intact hamsters. Melatonin (300 μg/day) also induced marked testicular regression in sexually mature intact and pinealectomized hamsters maintained on a photostimulatory LD 14:10 light cycle. The similar responses of pinealectomized and intact hamsters to melatonin treatment indicate that the effects of exogenous melatonin are not mediated via the pineal gland.

Original languageEnglish (US)
Pages (from-to)31-34
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Volume155
Issue number1
DOIs
StatePublished - May 1977

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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