Abstract
The administration of mela-tonin (12-150 μg/day) via subcutaneous Si-lastic capsules inhibited photic-induced testicular recrudescence to the same degree in both pinealectomized and intact hamsters. Melatonin (300 μg/day) also induced marked testicular regression in sexually mature intact and pinealectomized hamsters maintained on a photostimulatory LD 14:10 light cycle. The similar responses of pinealectomized and intact hamsters to melatonin treatment indicate that the effects of exogenous melatonin are not mediated via the pineal gland.
Original language | English (US) |
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Pages (from-to) | 31-34 |
Number of pages | 4 |
Journal | Proceedings of the Society for Experimental Biology and Medicine |
Volume | 155 |
Issue number | 1 |
DOIs | |
State | Published - May 1977 |
Funding
This investigation was supported by NSF Research Grant PCM-09955, NIH Grant 09885, and by a grant from the Office of Research and Sponsored Programs, Northwestern University.
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology