TY - JOUR
T1 - Antiphospholipid antibody syndrome secondary to trimethoprim/ sulfamethoxazole
AU - Silverberg, Jonathan I.
AU - Votava, Henry J.
AU - Smith, Barry L.
PY - 2012/9
Y1 - 2012/9
N2 - Antiphospholipid antibody syndrome (APS) results from autoantibodies to cell surface phospholipids or phospholipid-binding proteins resulting in clotting anomalies and can have devastating sequelae, including stroke, deep venous thrombosis, pulmonary embolism, and recurrent spontaneous abortions. However, cutaneous manifestations are the first sign of APS in up to 41% of patients. We present a case report of APS that developed several days after taking trimethoprim/sulfamethoxazole. The clinical and pathological features of this unique presentation, differential diagnoses, and treatments are discussed.
AB - Antiphospholipid antibody syndrome (APS) results from autoantibodies to cell surface phospholipids or phospholipid-binding proteins resulting in clotting anomalies and can have devastating sequelae, including stroke, deep venous thrombosis, pulmonary embolism, and recurrent spontaneous abortions. However, cutaneous manifestations are the first sign of APS in up to 41% of patients. We present a case report of APS that developed several days after taking trimethoprim/sulfamethoxazole. The clinical and pathological features of this unique presentation, differential diagnoses, and treatments are discussed.
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M3 - Article
C2 - 23135659
AN - SCOPUS:84867472433
SN - 1545-9616
VL - 11
SP - 1117
EP - 1118
JO - Journal of Drugs in Dermatology
JF - Journal of Drugs in Dermatology
IS - 9
ER -