TY - JOUR
T1 - Antipsychotic drugs and safety concerns for breast-feeding infants
AU - Parikh, Tapan
AU - Goyal, Dharmendra
AU - Scarff, Jonathan R.
AU - Lippmann, Steven
N1 - Publisher Copyright:
Copyright © 2014 by The Southern Medical Association.
Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 2014
Y1 - 2014
N2 - Antipsychotic drugs prescribed to treat psychiatric symptoms during the postpartumperiod are secreted into breastmilk. Because breast-feeding is crucial to infant development, it is important to select a medication that poses the fewest adverse consequences. Aripiprazole, haloperidol, perphenazine, and trifluoperazine demonstrate no known developmental dangers. Olanzapine, quetiapine, and risperidone are cited as safe, although monitoring is recommended. Chlorpromazine and clozapine may induce developmental concerns. There are limited safety data for asenapine, fluphenazine, iloperidone, loxapine, lurasidone, paliperidone, pimozide, thioridazine, thiothixene, and ziprasidone. Clinicians should choose medications considered to be the safest and prescribe them at the lowest effective doses
AB - Antipsychotic drugs prescribed to treat psychiatric symptoms during the postpartumperiod are secreted into breastmilk. Because breast-feeding is crucial to infant development, it is important to select a medication that poses the fewest adverse consequences. Aripiprazole, haloperidol, perphenazine, and trifluoperazine demonstrate no known developmental dangers. Olanzapine, quetiapine, and risperidone are cited as safe, although monitoring is recommended. Chlorpromazine and clozapine may induce developmental concerns. There are limited safety data for asenapine, fluphenazine, iloperidone, loxapine, lurasidone, paliperidone, pimozide, thioridazine, thiothixene, and ziprasidone. Clinicians should choose medications considered to be the safest and prescribe them at the lowest effective doses
KW - Antipsychotic drugs
KW - Atypical antipsychotic medications
KW - Breast-feeding
KW - Lactation
KW - Typical antipsychotic agents
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U2 - 10.14423/SMJ.0000000000000190
DO - 10.14423/SMJ.0000000000000190
M3 - Review article
C2 - 25365434
AN - SCOPUS:84922393977
SN - 0038-4348
VL - 107
SP - 686
EP - 688
JO - Southern Medical Journal
JF - Southern Medical Journal
IS - 11
ER -