TY - JOUR
T1 - Apathy and associated factors in Mexican patients with Parkinson's disease
AU - Rodríguez-Violante, Mayela
AU - González-Latapi, Paulina
AU - Cervantes-Arriaga, Amin
AU - Martínez-Ramírez, Daniel
AU - Velázquez-Osuna, Salvador
AU - Camacho-Ordoñez, Azyadeh
PY - 2014/5
Y1 - 2014/5
N2 - Apathy is one of the most common behavioral disturbances in Parkinson's disease (PD) with a reported prevalence of 17-51 %. Apathy has been associated with depression, cognitive deficits, and poor quality of life. The objective of this study was to determine the prevalence of apathy in Mexican subjects with PD and its correlation with clinical and demographic characteristics. A cross-sectional, descriptive, and analytic study was carried out. Consecutive subjects with PD attending the National Institute of Neurology and Neurosurgery in Mexico City were included. Demographic and other relevant clinical data were collected. The Apathy Scale was applied to all subjects. A cut-off score of ≥14 was used. A total of 241 non-demented patients (52.7 % male) were included. Apathy was found in 43 % of subjects. Lower body mass index, older age of PD onset, cognitive decline and disease severity were all related to apathy. The use of dopamine agonists or rasagiline was more common in patients with low apathy scores. Our results show that the prevalence of apathy in Mexican subjects with PD is similar to other reports.
AB - Apathy is one of the most common behavioral disturbances in Parkinson's disease (PD) with a reported prevalence of 17-51 %. Apathy has been associated with depression, cognitive deficits, and poor quality of life. The objective of this study was to determine the prevalence of apathy in Mexican subjects with PD and its correlation with clinical and demographic characteristics. A cross-sectional, descriptive, and analytic study was carried out. Consecutive subjects with PD attending the National Institute of Neurology and Neurosurgery in Mexico City were included. Demographic and other relevant clinical data were collected. The Apathy Scale was applied to all subjects. A cut-off score of ≥14 was used. A total of 241 non-demented patients (52.7 % male) were included. Apathy was found in 43 % of subjects. Lower body mass index, older age of PD onset, cognitive decline and disease severity were all related to apathy. The use of dopamine agonists or rasagiline was more common in patients with low apathy scores. Our results show that the prevalence of apathy in Mexican subjects with PD is similar to other reports.
KW - Apathy
KW - Apathy Scale
KW - Body mass index
KW - Dopamine agonist
KW - Parkinson's disease
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U2 - 10.1007/s10072-013-1591-6
DO - 10.1007/s10072-013-1591-6
M3 - Article
C2 - 24306058
AN - SCOPUS:84901369007
SN - 1590-1874
VL - 35
SP - 729
EP - 734
JO - Neurological Sciences
JF - Neurological Sciences
IS - 5
ER -