Aplasia of the Optic Nerve: A Report of Seven Cases

Yujia Zhou; Maura E. Ryan; Marilyn B. Mets; Hawke H. Yoon; Bahram Rahmani; Sudhi P. Kurup

doi:10.1080/01658107.2019.1617320

Aplasia of the Optic Nerve: A Report of Seven Cases

Yujia Zhou, Maura E. Ryan, Marilyn B. Mets, Hawke H. Yoon, Bahram Rahmani, Sudhi P. Kurup^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Optic nerve aplasia (ONA) is a rare congenital anomaly with a limited number of published reports. A retrospective review was performed on seven patients with ONA seen during 2004–2017. Patient’s ocular and extraocular manifestations, imaging findings, and clinical course were described. Magnetic resonance imaging (MRI) showed anomalies of the optic chiasm and tracts and other central nervous system involvement. In conclusion, in addition to thorough ophthalmic examinations, MRI is important in evaluating and diagnosing ONA. The patients need to be monitored for both ocular and extraocular concerns.

Original language	English (US)
Pages (from-to)	332-338
Number of pages	7
Journal	Neuro-Ophthalmology
Volume	44
Issue number	5
DOIs	https://doi.org/10.1080/01658107.2019.1617320
State	Published - Sep 2 2020

Keywords

Optic nerve aplasia
congenital blindness
microphthalmia
retinal maldevelopment

ASJC Scopus subject areas

Ophthalmology
Clinical Neurology

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10.1080/01658107.2019.1617320

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title = "Aplasia of the Optic Nerve: A Report of Seven Cases",

abstract = "Optic nerve aplasia (ONA) is a rare congenital anomaly with a limited number of published reports. A retrospective review was performed on seven patients with ONA seen during 2004–2017. Patient{\textquoteright}s ocular and extraocular manifestations, imaging findings, and clinical course were described. Magnetic resonance imaging (MRI) showed anomalies of the optic chiasm and tracts and other central nervous system involvement. In conclusion, in addition to thorough ophthalmic examinations, MRI is important in evaluating and diagnosing ONA. The patients need to be monitored for both ocular and extraocular concerns.",

keywords = "Optic nerve aplasia, congenital blindness, microphthalmia, retinal maldevelopment",

author = "Yujia Zhou and Ryan, {Maura E.} and Mets, {Marilyn B.} and Yoon, {Hawke H.} and Bahram Rahmani and Kurup, {Sudhi P.}",

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AU - Rahmani, Bahram

AU - Kurup, Sudhi P.

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AB - Optic nerve aplasia (ONA) is a rare congenital anomaly with a limited number of published reports. A retrospective review was performed on seven patients with ONA seen during 2004–2017. Patient’s ocular and extraocular manifestations, imaging findings, and clinical course were described. Magnetic resonance imaging (MRI) showed anomalies of the optic chiasm and tracts and other central nervous system involvement. In conclusion, in addition to thorough ophthalmic examinations, MRI is important in evaluating and diagnosing ONA. The patients need to be monitored for both ocular and extraocular concerns.

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KW - retinal maldevelopment

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Aplasia of the Optic Nerve: A Report of Seven Cases

Abstract

Keywords

ASJC Scopus subject areas

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