Apoptosis signaling in lymphocytes

Research output: Contribution to journalArticlepeer-review

186 Scopus citations


Lymphocyte apoptosis is essential for proper function of the immune system. Among other functions, it is responsible for the homeostasis of immune cells and plays a key role in the elimination of autoreactive lymphocytes. Recently, progress has been made in the identification of genes that regulate apoptosis. Studies characterizing the basic apoptosis signaling machinery have begun to reveal the molecular control of processes that modulate lymphocyte apoptosis.

Original languageEnglish (US)
Pages (from-to)277-285
Number of pages9
JournalCurrent Opinion in Immunology
Issue number3
StatePublished - Jan 1 1999

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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