Application of color Doppler M-mode echocardiography in the assessment of ventricular diastolic function: Potential for quantitative analysis

J. D. Thomas*, M. J. Garcia, N. L. Greenberg

*Corresponding author for this work

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Color Doppler M-mode echocardiography provides a spatiotemporal map of blood distribution (v(s,t)) within the heart, with a typical temporal resolution of 5 ms, a spatial resolution of 300 μm, and a velocity resolution of 3 cm/s. M-mode echocardiographic data can be obtained along a streamline from the mid-left atrium to the mid-left ventricle from either the apical transthoracic window or the basal transesophageal window. A key parameter of the color Doppler M-mode is the transmitral propagation velocity, the slope of the leading edge of the M-mode derived E-wave. This propagation velocity is significantly less than the velocities measured within the E-wave by pulsed Doppler echocardiography and appears to provide important independent information about left ventricular filling pressures and diastolic function. Furthermore, color M-mode velocities can be processed quantitatively by the Euler equation to yield estimates of the small (< 2 mmHg) pressure gradients between the base and apex during filling, the first time such gradients have been measured noninvasively.

Original languageEnglish (US)
Pages (from-to)135-141
Number of pages7
JournalHeart and Vessels
Volume12
Issue numberSUPPL. 12
StatePublished - Dec 1 1997

Keywords

  • Diastolic function
  • Echocardiography
  • Hemodynamics
  • Image processing

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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