Applications of optical resonance to biological imaging and labelfree protein micro arrays

M. Selim Ünlü; I. E. Özkumur; J. Needham; D. A. Bergstein; B. B. Goldberg; A. Yalcin; P. Spuhler; R. Irani; C. DeLisi

doi:10.1109/iembs.2008.4649744

Applications of optical resonance to biological imaging and labelfree protein micro arrays

M. Selim Ünlü, I. E. Özkumur, J. Needham, D. A. Bergstein, B. B. Goldberg, A. Yalcin, P. Spuhler, R. Irani, C. DeLisi

Physics and Astronomy

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We present biological imaging and sensing methods based on optical resonance and interference. In fluorescence microscopy, our nanoscale imaging capability sheds light onto conformational changes of DNA, DNA-protein complexes and polymer coatings on a solid surface. Interference measurements on a layered substrate yield a labelfree sensing platform for protein binding in a high-throughput micro-array format.

Original language	English (US)
Title of host publication	Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
Publisher	IEEE Computer Society
Pages	2643
Number of pages	1
ISBN (Print)	9781424418152
DOIs	https://doi.org/10.1109/iembs.2008.4649744
State	Published - 2008
Event	30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, Canada Duration: Aug 20 2008 → Aug 25 2008

Publication series

Name	Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"

Other

Other	30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
Country	Canada
City	Vancouver, BC
Period	8/20/08 → 8/25/08

ASJC Scopus subject areas

Computer Vision and Pattern Recognition
Signal Processing
Biomedical Engineering
Health Informatics

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Ünlü, M. S., Özkumur, I. E., Needham, J., Bergstein, D. A., Goldberg, B. B., Yalcin, A., Spuhler, P., Irani, R., & DeLisi, C. (2008). Applications of optical resonance to biological imaging and labelfree protein micro arrays. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 (pp. 2643). [4649744] (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"). IEEE Computer Society. https://doi.org/10.1109/iembs.2008.4649744

Ünlü, M. Selim ; Özkumur, I. E. ; Needham, J. ; Bergstein, D. A. ; Goldberg, B. B. ; Yalcin, A. ; Spuhler, P. ; Irani, R. ; DeLisi, C. / Applications of optical resonance to biological imaging and labelfree protein micro arrays. Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08. IEEE Computer Society, 2008. pp. 2643 (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology").

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abstract = "We present biological imaging and sensing methods based on optical resonance and interference. In fluorescence microscopy, our nanoscale imaging capability sheds light onto conformational changes of DNA, DNA-protein complexes and polymer coatings on a solid surface. Interference measurements on a layered substrate yield a labelfree sensing platform for protein binding in a high-throughput micro-array format.",

author = "{\"U}nl{\"u}, {M. Selim} and {\"O}zkumur, {I. E.} and J. Needham and Bergstein, {D. A.} and Goldberg, {B. B.} and A. Yalcin and P. Spuhler and R. Irani and C. DeLisi",

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Ünlü, MS, Özkumur, IE, Needham, J, Bergstein, DA, Goldberg, BB, Yalcin, A, Spuhler, P, Irani, R & DeLisi, C 2008, Applications of optical resonance to biological imaging and labelfree protein micro arrays. in Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08., 4649744, Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology", IEEE Computer Society, pp. 2643, 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08, Vancouver, BC, Canada, 8/20/08. https://doi.org/10.1109/iembs.2008.4649744

Applications of optical resonance to biological imaging and labelfree protein micro arrays. / Ünlü, M. Selim; Özkumur, I. E.; Needham, J.; Bergstein, D. A.; Goldberg, B. B.; Yalcin, A.; Spuhler, P.; Irani, R.; DeLisi, C.

Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08. IEEE Computer Society, 2008. p. 2643 4649744 (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology").

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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T1 - Applications of optical resonance to biological imaging and labelfree protein micro arrays

AU - Ünlü, M. Selim

AU - Özkumur, I. E.

AU - Needham, J.

AU - Bergstein, D. A.

AU - Goldberg, B. B.

AU - Yalcin, A.

AU - Spuhler, P.

AU - Irani, R.

AU - DeLisi, C.

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AB - We present biological imaging and sensing methods based on optical resonance and interference. In fluorescence microscopy, our nanoscale imaging capability sheds light onto conformational changes of DNA, DNA-protein complexes and polymer coatings on a solid surface. Interference measurements on a layered substrate yield a labelfree sensing platform for protein binding in a high-throughput micro-array format.

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DO - 10.1109/iembs.2008.4649744

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BT - Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08

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Y2 - 20 August 2008 through 25 August 2008

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Ünlü MS, Özkumur IE, Needham J, Bergstein DA, Goldberg BB, Yalcin A et al. Applications of optical resonance to biological imaging and labelfree protein micro arrays. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08. IEEE Computer Society. 2008. p. 2643. 4649744. (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"). https://doi.org/10.1109/iembs.2008.4649744