Applications of optical resonance to biological imaging and label-free protein microarrays.

M. Selim Unlü; I. E. Ozkumur; J. Needham; D. A. Bergstein; B. B. Goldberg; A. Yalcin; P. Spuhler; R. Irani; C. DeLisi

Applications of optical resonance to biological imaging and label-free protein microarrays.

M. Selim Unlü^*, I. E. Ozkumur, J. Needham, D. A. Bergstein, B. B. Goldberg, A. Yalcin, P. Spuhler, R. Irani, C. DeLisi

^*Corresponding author for this work

Physics and Astronomy

Research output: Contribution to journal › Article › peer-review

Abstract

We present biological imaging and sensing methods based on optical resonance and interference. In fluorescence microscopy, our nanoscale imaging capability sheds light onto conformational changes of DNA, DNA-protein complexes and polymer coatings on a solid surface. Interference measurements on a layered substrate yield a label-free sensing platform for protein binding in a high-throughput micro-array format.

Original language	English (US)
Number of pages	1
Journal	Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
State	Published - Dec 1 2008

ASJC Scopus subject areas

Signal Processing
Biomedical Engineering
Computer Vision and Pattern Recognition
Health Informatics

Cite this

Unlü, M. S., Ozkumur, I. E., Needham, J., Bergstein, D. A., Goldberg, B. B., Yalcin, A., Spuhler, P., Irani, R., & DeLisi, C. (2008). Applications of optical resonance to biological imaging and label-free protein microarrays. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference.

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title = "Applications of optical resonance to biological imaging and label-free protein microarrays.",

abstract = "We present biological imaging and sensing methods based on optical resonance and interference. In fluorescence microscopy, our nanoscale imaging capability sheds light onto conformational changes of DNA, DNA-protein complexes and polymer coatings on a solid surface. Interference measurements on a layered substrate yield a label-free sensing platform for protein binding in a high-throughput micro-array format.",

author = "Unl{\"u}, {M. Selim} and Ozkumur, {I. E.} and J. Needham and Bergstein, {D. A.} and Goldberg, {B. B.} and A. Yalcin and P. Spuhler and R. Irani and C. DeLisi",

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language = "English (US)",

journal = "Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference",

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Unlü, MS, Ozkumur, IE, Needham, J, Bergstein, DA, Goldberg, BB, Yalcin, A, Spuhler, P, Irani, R & DeLisi, C 2008, 'Applications of optical resonance to biological imaging and label-free protein microarrays.', Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference.

Applications of optical resonance to biological imaging and label-free protein microarrays. / Unlü, M. Selim; Ozkumur, I. E.; Needham, J. et al.
In: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 01.12.2008.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Applications of optical resonance to biological imaging and label-free protein microarrays.

AU - Unlü, M. Selim

AU - Ozkumur, I. E.

AU - Needham, J.

AU - Bergstein, D. A.

AU - Goldberg, B. B.

AU - Yalcin, A.

AU - Spuhler, P.

AU - Irani, R.

AU - DeLisi, C.

PY - 2008/12/1

Y1 - 2008/12/1

N2 - We present biological imaging and sensing methods based on optical resonance and interference. In fluorescence microscopy, our nanoscale imaging capability sheds light onto conformational changes of DNA, DNA-protein complexes and polymer coatings on a solid surface. Interference measurements on a layered substrate yield a label-free sensing platform for protein binding in a high-throughput micro-array format.

AB - We present biological imaging and sensing methods based on optical resonance and interference. In fluorescence microscopy, our nanoscale imaging capability sheds light onto conformational changes of DNA, DNA-protein complexes and polymer coatings on a solid surface. Interference measurements on a layered substrate yield a label-free sensing platform for protein binding in a high-throughput micro-array format.

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M3 - Article

SN - 1557-170X

JO - Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference

JF - Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference

ER -

Applications of optical resonance to biological imaging and label-free protein microarrays.

Abstract

ASJC Scopus subject areas

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