TY - JOUR
T1 - Applications of the pattern variability index (σ(z)) to the quantification of dysmorphogenesis in the hand
AU - Garn, S. M.
AU - Leonard, W. R.
AU - Poznanski, A. K.
PY - 1987
Y1 - 1987
N2 - We have generated percentiles for the pattern variability index (σ(z)) of the hand in 1,088 normal infants, children, and adults and have analyzed pattern variability indices for 820 individuals representing 50 congenital malformation syndromes with respect to the normal percentiles. The majority of the affected individuals exhibited elevated σ(z) values for the hand, some vastly in excess of normal, while such syndromes as Down, Turner, and the Prader-Willi syndrome were low rather than high in pattern variability of the hand.
AB - We have generated percentiles for the pattern variability index (σ(z)) of the hand in 1,088 normal infants, children, and adults and have analyzed pattern variability indices for 820 individuals representing 50 congenital malformation syndromes with respect to the normal percentiles. The majority of the affected individuals exhibited elevated σ(z) values for the hand, some vastly in excess of normal, while such syndromes as Down, Turner, and the Prader-Willi syndrome were low rather than high in pattern variability of the hand.
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U2 - 10.1002/ajmg.1320270115
DO - 10.1002/ajmg.1320270115
M3 - Article
C2 - 3605192
AN - SCOPUS:0023267596
SN - 0148-7299
VL - 27
SP - 143
EP - 152
JO - American Journal of Medical Genetics
JF - American Journal of Medical Genetics
IS - 1
ER -