Applications of the pattern variability index (σ(z)) to the quantification of dysmorphogenesis in the hand

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

We have generated percentiles for the pattern variability index (σ(z)) of the hand in 1,088 normal infants, children, and adults and have analyzed pattern variability indices for 820 individuals representing 50 congenital malformation syndromes with respect to the normal percentiles. The majority of the affected individuals exhibited elevated σ(z) values for the hand, some vastly in excess of normal, while such syndromes as Down, Turner, and the Prader-Willi syndrome were low rather than high in pattern variability of the hand.

Original languageEnglish (US)
Pages (from-to)143-152
Number of pages10
JournalAmerican Journal of Medical Genetics
Volume27
Issue number1
DOIs
StatePublished - 1987

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

Fingerprint Dive into the research topics of 'Applications of the pattern variability index (σ(z)) to the quantification of dysmorphogenesis in the hand'. Together they form a unique fingerprint.

Cite this