Applications of Zr-catalyzed carbomagnesation and Mo-catalyzed macrocyclic ring closing metathesis in asymmetric synthesis. Enantioselective synthesis of Sch 38516 (Fluvirucin B1)

K. A. Scheidt*, W. R. Roush, A. F. Houri, D. S. La, D. A. Cogan, G. E. Hofilena, A. H. Hoveyda

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

For the synthesis of the antifungal agent Sch 38516. Hoveyda has employed a number of important transition metal-catalyzed reactions, including a ring-closing metathesis reaction to close the macrocycle present in this natural product.

Original languageEnglish (US)
Pages (from-to)522-530
Number of pages9
JournalChemtracts
Volume11
Issue number7
StatePublished - Jun 1 1998

ASJC Scopus subject areas

  • Chemistry(all)
  • Biochemistry
  • Molecular Biology

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