Approach to Patients with Eosinophilia

Research output: Contribution to journalReview article

Abstract

Physicians may encounter blood or tissue eosinophilia through a routine complete blood count with differential or a tissue pathology report. In this article, the basic biology of eosinophils is reviewed and definitions of blood eosinophilia, as well as the challenges of defining tissue eosinophilia, are discussed. Conditions associated with eosinophilia are briefly discussed as well as a general approach to evaluating eosinophilia. Future challenges include determining which eosinophil-associated diseases benefit from eosinophil-targeted therapy and identifying biomarkers for disease activity and diagnosis.

Original languageEnglish (US)
Pages (from-to)1-14
Number of pages14
JournalMedical Clinics of North America
Volume104
Issue number1
DOIs
StatePublished - Jan 2020

Fingerprint

Eosinophilia
Eosinophils
Blood Cell Count
Biomarkers
Pathology
Physicians

Keywords

  • Biologics
  • Corticosteroids
  • Eosinophil
  • Eosinophil granule proteins
  • Hypereosinophilia
  • IL-5

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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abstract = "Physicians may encounter blood or tissue eosinophilia through a routine complete blood count with differential or a tissue pathology report. In this article, the basic biology of eosinophils is reviewed and definitions of blood eosinophilia, as well as the challenges of defining tissue eosinophilia, are discussed. Conditions associated with eosinophilia are briefly discussed as well as a general approach to evaluating eosinophilia. Future challenges include determining which eosinophil-associated diseases benefit from eosinophil-targeted therapy and identifying biomarkers for disease activity and diagnosis.",
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Approach to Patients with Eosinophilia. / Kuang, Fei Li.

In: Medical Clinics of North America, Vol. 104, No. 1, 01.2020, p. 1-14.

Research output: Contribution to journalReview article

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N2 - Physicians may encounter blood or tissue eosinophilia through a routine complete blood count with differential or a tissue pathology report. In this article, the basic biology of eosinophils is reviewed and definitions of blood eosinophilia, as well as the challenges of defining tissue eosinophilia, are discussed. Conditions associated with eosinophilia are briefly discussed as well as a general approach to evaluating eosinophilia. Future challenges include determining which eosinophil-associated diseases benefit from eosinophil-targeted therapy and identifying biomarkers for disease activity and diagnosis.

AB - Physicians may encounter blood or tissue eosinophilia through a routine complete blood count with differential or a tissue pathology report. In this article, the basic biology of eosinophils is reviewed and definitions of blood eosinophilia, as well as the challenges of defining tissue eosinophilia, are discussed. Conditions associated with eosinophilia are briefly discussed as well as a general approach to evaluating eosinophilia. Future challenges include determining which eosinophil-associated diseases benefit from eosinophil-targeted therapy and identifying biomarkers for disease activity and diagnosis.

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KW - Hypereosinophilia

KW - IL-5

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