Approach to treatment of the patient with metabolic syndrome: Lifestyle therapy

Neil J. Stone*, David Saxon

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

60 Scopus citations


The National Cholesterol Education Program's Adult Treatment Panel III definition of the metabolic syndrome identifies those at high risk for diabetes mellitus and/or a cardiac event by clustering a number of easily measured clinical findings, including abdominal obesity, elevated plasma levels of triglycerides, low plasma levels of high-density lipoprotein cholesterol, elevated fasting blood glucose, and elevated blood pressure. The presence of <3 of these 5 risk factors justifies a diagnosis of the metabolic syndrome. This article focuses on root causes of the syndrome (atherogenic diet, sedentary lifestyle, and overweight/obesity) and highlights recent studies that demonstrate the effectiveness of therapeutic lifestyle changes in improving or preventing the components of the metabolic syndrome. We offer a practical approach with a focus that embraces not only patients, but also physicians and healthcare professionals as well as the larger healthcare system.

Original languageEnglish (US)
Pages (from-to)15-21
Number of pages7
JournalAmerican Journal of Cardiology
Issue number4 SUPPL.
StatePublished - Aug 22 2005

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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