Aquagenic palmoplantar keratoderma

Albert C. Yan*, Sumaira Z. Aasi, William J. Alms, William D. James, Warren R. Heymann, Amy Paller, Paul J. Honig

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

116 Scopus citations


Aquagenic palmoplantar keratoderma is an acquired condition characterized by burning and edema limited to the hands after brief immersion in water. The 3 patients described possess a striking similarity to those with transient reactive papulotranslucent acrokeratoderma. All 3 patients manifested the "hand-in-the-bucket" sign, having presented to a physician with a hand immersed in a bucket of water to more promptly demonstrate the physical findings. Aluminum chloride hexahydrate represents a potentially valuable therapeutic option for this unusual condition.

Original languageEnglish (US)
Pages (from-to)696-699
Number of pages4
JournalJournal of the American Academy of Dermatology
Issue number4
StatePublished - 2001

ASJC Scopus subject areas

  • Dermatology


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