Aqueous humor formation in fish: The role of sodium-potassium-activated adenosine triphosphatase in the spiny dogfish (Squalus acanthias) eye

Lee M. Jampol; John N. Forrest

doi:10.1016/0014-4835(72)90113-3

Aqueous humor formation in fish: The role of sodium-potassium-activated adenosine triphosphatase in the spiny dogfish (Squalus acanthias) eye

Lee M. Jampol^*, John N. Forrest

^*Corresponding author for this work

Ophthalmology

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

The anatomy of the fish ciliary body and the distribution of sodium-potassium-activated adenosine triphosphatase in the elasmobranch (Squalus acanthias) eye were studied in an attempt to localize the site of formation of aqueous humor. Both teleosts and elasmobranchs have a ciliary body with a nonpigmented and pigmented epithelium similar to the mammalian pars plana. The fish ciliary body has no processes and little or no smooth muscle. Sodium-potassium-activated adenosine triphosphatase was found in significant levels in the elasmobranch retina, ciliary body and brain, while the iris had little activity. If the elasmobranch eye is similar to the mammalian eye and sodium transport is involved in aqueous humor formation, the ciliary body seems the most likely site of transport.

Original language	English (US)
Pages (from-to)	315-318,IN27-IN35,319
Journal	Experimental eye research
Volume	13
Issue number	3
DOIs	https://doi.org/10.1016/0014-4835(72)90113-3
State	Published - May 1972

ASJC Scopus subject areas

Ophthalmology
Sensory Systems
Cellular and Molecular Neuroscience

Access to Document

10.1016/0014-4835(72)90113-3

Cite this

@article{cf601162bb3a4a5487d374a3272b6e38,

title = "Aqueous humor formation in fish: The role of sodium-potassium-activated adenosine triphosphatase in the spiny dogfish (Squalus acanthias) eye",

abstract = "The anatomy of the fish ciliary body and the distribution of sodium-potassium-activated adenosine triphosphatase in the elasmobranch (Squalus acanthias) eye were studied in an attempt to localize the site of formation of aqueous humor. Both teleosts and elasmobranchs have a ciliary body with a nonpigmented and pigmented epithelium similar to the mammalian pars plana. The fish ciliary body has no processes and little or no smooth muscle. Sodium-potassium-activated adenosine triphosphatase was found in significant levels in the elasmobranch retina, ciliary body and brain, while the iris had little activity. If the elasmobranch eye is similar to the mammalian eye and sodium transport is involved in aqueous humor formation, the ciliary body seems the most likely site of transport.",

author = "Jampol, {Lee M.} and Forrest, {John N.}",

note = "Funding Information: I wish to thank Drs Marvin Sears, Daniel Albert, and Franklin Epstein for their help in preparing this manuscript and Mrs Indu Bhatt for technical assistancein preparing the tissue sections. This investigation wass upportedi n part by the Connecticut Lions Eye ResearchF ounda-tion, Inc; by PHS grants (EY-00002-10) from the National Eye Institute, and (HE-00834) from the National Heart Institute, U.S. Public Health Service; and by a grant (GB-8862) to the Mt. Desert Island Biology Laboratory from The National Science Foundation.",

year = "1972",

month = may,

doi = "10.1016/0014-4835(72)90113-3",

language = "English (US)",

volume = "13",

pages = "315--318,IN27--IN35,319",

journal = "Experimental Eye Research",

issn = "0014-4835",

publisher = "Academic Press Inc.",

number = "3",

}

TY - JOUR

T1 - Aqueous humor formation in fish

T2 - The role of sodium-potassium-activated adenosine triphosphatase in the spiny dogfish (Squalus acanthias) eye

AU - Jampol, Lee M.

AU - Forrest, John N.

N1 - Funding Information: I wish to thank Drs Marvin Sears, Daniel Albert, and Franklin Epstein for their help in preparing this manuscript and Mrs Indu Bhatt for technical assistancein preparing the tissue sections. This investigation wass upportedi n part by the Connecticut Lions Eye ResearchF ounda-tion, Inc; by PHS grants (EY-00002-10) from the National Eye Institute, and (HE-00834) from the National Heart Institute, U.S. Public Health Service; and by a grant (GB-8862) to the Mt. Desert Island Biology Laboratory from The National Science Foundation.

PY - 1972/5

Y1 - 1972/5

N2 - The anatomy of the fish ciliary body and the distribution of sodium-potassium-activated adenosine triphosphatase in the elasmobranch (Squalus acanthias) eye were studied in an attempt to localize the site of formation of aqueous humor. Both teleosts and elasmobranchs have a ciliary body with a nonpigmented and pigmented epithelium similar to the mammalian pars plana. The fish ciliary body has no processes and little or no smooth muscle. Sodium-potassium-activated adenosine triphosphatase was found in significant levels in the elasmobranch retina, ciliary body and brain, while the iris had little activity. If the elasmobranch eye is similar to the mammalian eye and sodium transport is involved in aqueous humor formation, the ciliary body seems the most likely site of transport.

AB - The anatomy of the fish ciliary body and the distribution of sodium-potassium-activated adenosine triphosphatase in the elasmobranch (Squalus acanthias) eye were studied in an attempt to localize the site of formation of aqueous humor. Both teleosts and elasmobranchs have a ciliary body with a nonpigmented and pigmented epithelium similar to the mammalian pars plana. The fish ciliary body has no processes and little or no smooth muscle. Sodium-potassium-activated adenosine triphosphatase was found in significant levels in the elasmobranch retina, ciliary body and brain, while the iris had little activity. If the elasmobranch eye is similar to the mammalian eye and sodium transport is involved in aqueous humor formation, the ciliary body seems the most likely site of transport.

UR - http://www.scopus.com/inward/record.url?scp=0015335783&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0015335783&partnerID=8YFLogxK

U2 - 10.1016/0014-4835(72)90113-3

DO - 10.1016/0014-4835(72)90113-3

M3 - Article

C2 - 4260556

AN - SCOPUS:0015335783

VL - 13

SP - 315-318,IN27-IN35,319

JO - Experimental Eye Research

JF - Experimental Eye Research

SN - 0014-4835

IS - 3

ER -

Aqueous humor formation in fish: The role of sodium-potassium-activated adenosine triphosphatase in the spiny dogfish (Squalus acanthias) eye

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this