Abstract
NONRACE-SPECIFIC DISEASE RESISTANCE (NDR1)is a widely characterized gene that plays a key role in defense against multiple bacterial, fungal, oomycete and nematode plant pathogens. NDR1 is required for activation of resistance by multiple NB and LRR-containing (NLR)protein immune sensors and contributes to basal defense. The role of NDR1 in positively regulating salicylic acid (SA)-mediated plant defense responses is well documented. However, ndr1-1 plants flower earlier and show accelerated development in comparison to wild type (WT)Arabidopsis plants, indicating that NDR1 is a negative regulator of flowering and growth. Exogenous application of gibberellic acid (GA)further accelerates the early flowering phenotype in ndr1-1 plants, while the GA biosynthesis inhibitor paclobutrazol attenuated the early flowering phenotype of ndr1-1, but not to WT levels, suggesting partial resistance to paclobutrazol and enhanced GA response in ndr1-1 plants. Mass spectroscopy analyses confirmed that ndr1-1 plants have 30–40% higher levels of GA3 and GA4, while expression of various GA metabolic genes and major flowering regulatory genes is also altered in the ndr1-1 mutant. Taken together this study provides evidence of crosstalk between the ndr1-1-mediated defense and GA-regulated developmental programs in plants.
Original language | English (US) |
---|---|
Pages (from-to) | 200-213 |
Number of pages | 14 |
Journal | Plant Science |
Volume | 285 |
DOIs | |
State | Published - Aug 2019 |
Externally published | Yes |
Keywords
- Arabidopsis NDR1
- Defense and development
- Disease resistance
- Flowering time
- Gibberellic acid
- Salicylic acid
ASJC Scopus subject areas
- Genetics
- Agronomy and Crop Science
- Plant Science