Are MicroRNAs Key to Developing Biomarkers for Cutaneous T-Cell Lymphoma?

Maria Estela Martinez-Escala, Jaehyuk Choi

Research output: Contribution to journalComment/debate

1 Citation (Scopus)

Abstract

MicroRNAs are noncoding molecules that induce epigenetic modulation, and they have been involved in tumorigenesis of solid and hematologic malignancies, including cutaneous T-cell lymphoma. MicroRNAs appear to play a role in cutaneous T-cell lymphoma pathogenesis and in disease progression. We comment on recent efforts to develop microRNA classifiers that improve cutaneous T-cell lymphoma diagnosis and predict disease course.

Original languageEnglish (US)
Pages (from-to)1906-1908
Number of pages3
JournalJournal of Investigative Dermatology
Volume138
Issue number9
DOIs
StatePublished - Sep 1 2018

Fingerprint

Cutaneous T-Cell Lymphoma
T-cells
Biomarkers
MicroRNAs
Hematologic Neoplasms
Epigenomics
Disease Progression
Carcinogenesis
Classifiers
Modulation
Molecules

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology

Cite this

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abstract = "MicroRNAs are noncoding molecules that induce epigenetic modulation, and they have been involved in tumorigenesis of solid and hematologic malignancies, including cutaneous T-cell lymphoma. MicroRNAs appear to play a role in cutaneous T-cell lymphoma pathogenesis and in disease progression. We comment on recent efforts to develop microRNA classifiers that improve cutaneous T-cell lymphoma diagnosis and predict disease course.",
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Are MicroRNAs Key to Developing Biomarkers for Cutaneous T-Cell Lymphoma? / Martinez-Escala, Maria Estela; Choi, Jaehyuk.

In: Journal of Investigative Dermatology, Vol. 138, No. 9, 01.09.2018, p. 1906-1908.

Research output: Contribution to journalComment/debate

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AU - Choi, Jaehyuk

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N2 - MicroRNAs are noncoding molecules that induce epigenetic modulation, and they have been involved in tumorigenesis of solid and hematologic malignancies, including cutaneous T-cell lymphoma. MicroRNAs appear to play a role in cutaneous T-cell lymphoma pathogenesis and in disease progression. We comment on recent efforts to develop microRNA classifiers that improve cutaneous T-cell lymphoma diagnosis and predict disease course.

AB - MicroRNAs are noncoding molecules that induce epigenetic modulation, and they have been involved in tumorigenesis of solid and hematologic malignancies, including cutaneous T-cell lymphoma. MicroRNAs appear to play a role in cutaneous T-cell lymphoma pathogenesis and in disease progression. We comment on recent efforts to develop microRNA classifiers that improve cutaneous T-cell lymphoma diagnosis and predict disease course.

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