Are the Duke criteria superior to the Beth Israel criteria for the diagnosis of infective endocarditis in children?

Janet A. Stockheim*, Ellen G. Chadwick, Susan Kessler, Michael Amer, Nahed Abdel-Haq, Adnan S. Dajani, Stanford T. Shulman

*Corresponding author for this work

Research output: Contribution to journalArticle

70 Scopus citations

Abstract

Accurate diagnosis of infective endocarditis may be difficult. The Beth Israel criteria and the newer Duke criteria assign probability to the diagnosis of infective endocarditis on the basis of the presence of common features and manifestations. We reviewed 111 cases of pediatric infective endocarditis diagnosed and treated over 19 years. Each case was classified by the two criteria, and the results were compared. Of 111 cases, 73 (66%) and 18 (16%) were classified as definite by the Duke criteria and the Beth Israel criteria, respectively. No cases were rejected by the Duke criteria, while 21 (19%) of 111 were rejected by the Beth Israel criteria. In 18 pathologically proven cases, reanalysis without pathological data showed that the Duke criteria had significantly greater sensitivity (83%) than the Beth Israel criteria (67%) (P < .03). Echocardiographic evidence was required in 22 cases for definite classification by the Duke criteria; none were rejected, however, when echocardiographic findings were ignored. Our results suggest that the Duke criteria are superior to the Beth Israel criteria for the diagnosis of pediatric infective endocarditis.

Original languageEnglish (US)
Pages (from-to)1451-1456
Number of pages6
JournalClinical Infectious Diseases
Volume27
Issue number6
DOIs
StatePublished - Dec 1998

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Are the Duke criteria superior to the Beth Israel criteria for the diagnosis of infective endocarditis in children?'. Together they form a unique fingerprint.

  • Cite this