Are women who have had a preterm twin delivery at greater risk of preterm birth in a subsequent singleton pregnancy?

Francesca L. Facco*, Kate Nash, William A. Grobman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Objective: The purpose of this study was to determine whether preterm birth of twins is associated with an increased risk of preterm birth in a subsequent singleton pregnancy. Study Design: All patients who delivered a twin gestation and a subsequent singleton pregnancy at Northwestern Memorial Hospital during a 10-year period were identified. We used a cohort study design, comparing the outcomes of the singleton pregnancies in women with preterm twin deliveries to those pregnancies with term twin deliveries. Results: One hundred sixty-seven women delivered twins followed by a singleton pregnancy. Women whose twin delivery was preterm (n = 99) were more likely than those who had delivered a term twin pregnancy (n = 68) to deliver a subsequent preterm singleton pregnancy (13.1% vs 2.9%; odds ratio, 5.0; 95% CI, 1.1, 22.9). Conclusion: Preterm birth of twins is associated with an increased risk of preterm delivery in a subsequent singleton pregnancy.

Original languageEnglish (US)
Pages (from-to)253.e1-253.e3
JournalAmerican journal of obstetrics and gynecology
Volume197
Issue number3
DOIs
StatePublished - Sep 2007

Keywords

  • premature
  • preterm birth
  • twin gestation

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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