Arginine vasotocin from the pituitary gland of the lamprey (Petromyzon marinus): Isolation and amino acid sequence

Timothy F. Lane, Stacia A. Sower, Hiroshi Kawauchi*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

Arginine vasotocin (AVT) was isolated from extracts of sea lamprey pituitary glands (Petromyzon marinus). The amino acid sequence Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2 is identical to the molecule isolated from teleosts and tetrapods. The total yield was estimated to be 9.6 pmol per gland. No evidence could be found for the existence of a second neurohypophyseal nonapeptide in the lamprey pituitary.

Original languageEnglish (US)
Pages (from-to)152-157
Number of pages6
JournalGeneral and Comparative Endocrinology
Volume70
Issue number1
DOIs
StatePublished - Apr 1988
Externally publishedYes

Funding

This work was conducted to T.F.L. while he was a visiting scientist at The School of Fisheries Sciences, Kitasato University. The work was supported by the Great Lakes Fisheries Commission and by a NSF grant (DCB-8602907) to S.A.S. We thank Drs. P. Swanson and W. Dickhoff for critically reading the manuscript, and M. Nozaki for many helpful comments.

ASJC Scopus subject areas

  • Endocrinology
  • Animal Science and Zoology

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