Argon beam coagulation as an adjuvant for local control of giant cell tumor

Valerae O. Lewis*, Anthony Wei, Tito Mendoza, Frank Primus, Terrance Peabody, Michael A. Simon

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

49 Scopus citations


The argon beam coagulator is gaining popularity as an adjuvant therapy for treatment of giant cell tumors of bone. However, the effectiveness and functional implications of this treatment have not been assessed. To determine whether the argon beam coagulator could be a viable adjuvant treatment option, we examined the recurrence rate and functional outcome of patients with giant cell tumors who were treated with the argon beam coagulator, as an adjuvant to curettage and cementation. Thirty-seven patients who received argon beam coagulation as an adjuvant treatment for giant cell tumors diagnosed between 1993 and 2000 were identified. The median age of the patients was 32 years (range, 16-64 years). The mean followup was 73.7 months (range, 0.5-108 months). Three patients had osseous recurrences (8.3%) and one had a soft tissue recurrence. The 5-year Kaplan-Meier disease-free survival estimate was 87.2% (95% confidence interval, range, 76.3-99.8). No patient had radiographic evidence of arthritis. The average Musculoskeletal Tumor Society score was 28. Short form-36 evaluation showed no change in functional or mental perception in these patients compared with US norms. These data suggest argon beam coagulation as an adjuvant therapy is associated with in a low rate of local recurrence and is a reasonable adjuvant treatment option.

Original languageEnglish (US)
Pages (from-to)192-197
Number of pages6
JournalClinical Orthopaedics and Related Research
Issue number454
StatePublished - Jan 1 2007

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Fingerprint Dive into the research topics of 'Argon beam coagulation as an adjuvant for local control of giant cell tumor'. Together they form a unique fingerprint.

Cite this