Arrays of Colloidal Single Crystals Engineered with DNA in Lithographically Defined Microwells

Alexa M. Wong, Kwanghwi Je, Cindy Y. Zheng, Liban Jibril, Ziyi Miao, Sharon C. Glotzer*, Chad A. Mirkin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Lithographically defined microwell templates are used to study DNA-guided colloidal crystal assembly parameters, including superlattice position, habit orientation, and size, in an effort to increase our understanding of the crystallization process. In addition to enabling the synthesis of arrays of individual superlattices in arbitrary predefined patterns, the technique allows one to study the growth pathways of the crystals via ex situ scanning electron microscopy. Importantly, a Volmer-Weber (VM) (island formation)-like growth mode is identified, which has been reproduced via simulations. Notably, both experiment and simulation reveal that the crystallites merge and reorient within the microwells that defined the crystal growth to form single-crystalline structures, an observation not common for VM pathways. The control afforded by this platform will facilitate efforts in constructing metamaterials from colloidal crystals as well as their integration into optical devices and applications.

Original languageEnglish (US)
Pages (from-to)116-123
Number of pages8
JournalNano letters
Issue number1
StatePublished - Jan 11 2023


  • DNA-mediated assembly
  • colloidal crystals
  • confinement
  • crystallization
  • nanoparticles

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Mechanical Engineering
  • Bioengineering
  • General Chemistry
  • General Materials Science


Dive into the research topics of 'Arrays of Colloidal Single Crystals Engineered with DNA in Lithographically Defined Microwells'. Together they form a unique fingerprint.

Cite this