Arteriolar Occlusive Diseases of the Macula

L. M. Jampol*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Occlusion of retinal precapillary arterioles may be related to vascular endothelial damage, embolization, vasculitis, and other factors. Following acute retinal precapillary arteriolar occlusion in the macular area, inhibition of axoplasmic transport results in the formation of cotton-wool patches. A variable loss of retinal function occurs. During the subacute phase, reperfusion of the vascular bed is usually seen with a gradual fading of the cotton-wool patch. In the chronic phase, the only sign of the infarction may be a loss of inner retinal substance with an irregularity of the light reflex from the internal limiting membrane, the retinal depression sign. The characteristics of retinal precapillary arteriolar occlusions are reviewed and specific features of hypertensive retinopathy, talc retinopathy, and sickle cell retinopathy are discussed.

Original languageEnglish (US)
Pages (from-to)534-539
Number of pages6
Issue number5
StatePublished - 1983


  • arteriole
  • axoplasmic transport
  • cotton-wool patch
  • hypertension
  • ischemia
  • precapillary
  • sickle cell retinopathy
  • talc retinopathy

ASJC Scopus subject areas

  • Ophthalmology


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