TY - JOUR
T1 - Asbestos catalyzes the formation of the 6-oxobenzo[a]pyrene radical from 6-hydroxybenzo[a]pyrene
AU - Graceffa, Philip
AU - Weitzman, Sigmund A.
PY - 1987/1/1
Y1 - 1987/1/1
N2 - Crocidolite asbestos catalyzes the oxidation of 6-hyroxybenzo[a]pyrene, a metabolite of benzo[a]pyrene, to the 6-oxobenzo[a]pyrene radical as determined by electron spin resonance spectroscopy. This may be a mechanism whereby inhaled asbestos enhances the incidence of lung cancer induced by cigarette smoke, which contains benzo[a]pyrene.
AB - Crocidolite asbestos catalyzes the oxidation of 6-hyroxybenzo[a]pyrene, a metabolite of benzo[a]pyrene, to the 6-oxobenzo[a]pyrene radical as determined by electron spin resonance spectroscopy. This may be a mechanism whereby inhaled asbestos enhances the incidence of lung cancer induced by cigarette smoke, which contains benzo[a]pyrene.
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U2 - 10.1016/0003-9861(87)90594-7
DO - 10.1016/0003-9861(87)90594-7
M3 - Article
C2 - 2821915
AN - SCOPUS:0023201544
VL - 257
SP - 481
EP - 484
JO - Archives of Biochemistry and Biophysics
JF - Archives of Biochemistry and Biophysics
SN - 0003-9861
IS - 2
ER -