@inbook{dd86bda74ca542f1bd782b496dca7575,
title = "Aspects of Prostaglandin Glycerol Ester Biology",
abstract = "The Cyclooxygenase enzymes (COX-1 and COX-2) incorporate 2 molecules of O2 into arachidonic acid (AA), resulting in an array of bioactive prostaglandins. However, much work has been done showing that COX-2 will perform this reaction on several different AA-containing molecules, most importantly, the endocannabinoid 2-arachidonoylglycerol (2-AG). The products of 2-AG oxygenation, prostaglandin glycerol esters (PG-Gs), are analogous to canonical prostaglandins. This chapter reviews the literature detailing the production, metabolism, and bioactivity of these compounds, as well as their detection in intact animals.",
keywords = "2-Arachidonoyl glycerol, Anandamide, Cannabinoid, COX-2, Cyclooxygenase, Endocannabinoid, Inflammation, Prostaglandin, Prostaglandin glyceryl ester, Transgenic mouse",
author = "Kingsley, {Philip J.} and Rouzer, {Carol A.} and Morgan, {Amanda J.} and Sachin Patel and Marnett, {Lawrence J.}",
note = "Publisher Copyright: {\textcopyright} 2019, Springer Nature Switzerland AG.",
year = "2019",
doi = "10.1007/978-3-030-21735-8_8",
language = "English (US)",
series = "Advances in Experimental Medicine and Biology",
publisher = "Springer New York LLC",
pages = "77--88",
booktitle = "Advances in Experimental Medicine and Biology",
}