Assembly and organization processes in DNA-directed colloidal crystallization

Robert J. Macfarlane; Byeongdu Lee; Haley D. Hill; Andrew J. Senesi; Soenke Seifert; Chad A. Mirkin

doi:10.1073/pnas.0900630106

Assembly and organization processes in DNA-directed colloidal crystallization

Robert J. Macfarlane, Byeongdu Lee, Haley D. Hill, Andrew J. Senesi, Soenke Seifert, Chad A. Mirkin

Chemistry

Research output: Contribution to journal › Article › peer-review

149 Scopus citations

Abstract

We present an analysis of the key steps involved in the DNA-directed assembly of nanoparticles into crystallites and polycrystalline aggregates. Additionally, the rate of crystal growth as a function of increased DNA linker length, solution temperature, and self-complementary versus non-self- complementary DNA linker strands (1- versus 2-component systems) has been studied. The data show that the crystals grow via a 3-step process: an initial "random binding" phase resulting in disordered DNA-AuNP aggregates, followed by localized reorganization and subsequent growth of crystalline domain size, where the resulting crystals are well-ordered at all subsequent stages of growth.

Original language	English (US)
Pages (from-to)	10493-10498
Number of pages	6
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	106
Issue number	26
DOIs	https://doi.org/10.1073/pnas.0900630106
State	Published - Jun 30 2009

Keywords

DNA materials
SAXS
Self assembly

ASJC Scopus subject areas

General

Access to Document

10.1073/pnas.0900630106

Cite this

@article{71a775ab3a01494bb6e03749ee5d21c0,

title = "Assembly and organization processes in DNA-directed colloidal crystallization",

abstract = "We present an analysis of the key steps involved in the DNA-directed assembly of nanoparticles into crystallites and polycrystalline aggregates. Additionally, the rate of crystal growth as a function of increased DNA linker length, solution temperature, and self-complementary versus non-self- complementary DNA linker strands (1- versus 2-component systems) has been studied. The data show that the crystals grow via a 3-step process: an initial {"}random binding{"} phase resulting in disordered DNA-AuNP aggregates, followed by localized reorganization and subsequent growth of crystalline domain size, where the resulting crystals are well-ordered at all subsequent stages of growth.",

keywords = "DNA materials, SAXS, Self assembly",

author = "Macfarlane, {Robert J.} and Byeongdu Lee and Hill, {Haley D.} and Senesi, {Andrew J.} and Soenke Seifert and Mirkin, {Chad A.}",

year = "2009",

month = jun,

day = "30",

doi = "10.1073/pnas.0900630106",

language = "English (US)",

volume = "106",

pages = "10493--10498",

journal = "Proceedings of the National Academy of Sciences of the United States of America",

issn = "0027-8424",

publisher = "National Academy of Sciences",

number = "26",

}

TY - JOUR

T1 - Assembly and organization processes in DNA-directed colloidal crystallization

AU - Macfarlane, Robert J.

AU - Lee, Byeongdu

AU - Hill, Haley D.

AU - Senesi, Andrew J.

AU - Seifert, Soenke

AU - Mirkin, Chad A.

PY - 2009/6/30

Y1 - 2009/6/30

N2 - We present an analysis of the key steps involved in the DNA-directed assembly of nanoparticles into crystallites and polycrystalline aggregates. Additionally, the rate of crystal growth as a function of increased DNA linker length, solution temperature, and self-complementary versus non-self- complementary DNA linker strands (1- versus 2-component systems) has been studied. The data show that the crystals grow via a 3-step process: an initial "random binding" phase resulting in disordered DNA-AuNP aggregates, followed by localized reorganization and subsequent growth of crystalline domain size, where the resulting crystals are well-ordered at all subsequent stages of growth.

AB - We present an analysis of the key steps involved in the DNA-directed assembly of nanoparticles into crystallites and polycrystalline aggregates. Additionally, the rate of crystal growth as a function of increased DNA linker length, solution temperature, and self-complementary versus non-self- complementary DNA linker strands (1- versus 2-component systems) has been studied. The data show that the crystals grow via a 3-step process: an initial "random binding" phase resulting in disordered DNA-AuNP aggregates, followed by localized reorganization and subsequent growth of crystalline domain size, where the resulting crystals are well-ordered at all subsequent stages of growth.

KW - DNA materials

KW - SAXS

KW - Self assembly

UR - http://www.scopus.com/inward/record.url?scp=67649795148&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67649795148&partnerID=8YFLogxK

U2 - 10.1073/pnas.0900630106

DO - 10.1073/pnas.0900630106

M3 - Article

C2 - 19549828

AN - SCOPUS:67649795148

SN - 0027-8424

VL - 106

SP - 10493

EP - 10498

JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

IS - 26

ER -

Assembly and organization processes in DNA-directed colloidal crystallization

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this