Assessing the spatial heterogeneity in black-white differences in optimal cardiovascular health and the impact of individual- and neighborhood-level risk factors: The Multi-Ethnic Study of Atherosclerosis (MESA)

Loni Philip Tabb; Leslie A. McClure; Angel Ortiz; Steven Melly; Miranda R. Jones; Kiarri N. Kershaw; Ana V.Diez Roux

doi:10.1016/j.sste.2020.100332

Assessing the spatial heterogeneity in black-white differences in optimal cardiovascular health and the impact of individual- and neighborhood-level risk factors: The Multi-Ethnic Study of Atherosclerosis (MESA)

Loni Philip Tabb^*, Leslie A. McClure, Angel Ortiz, Steven Melly, Miranda R. Jones, Kiarri N. Kershaw, Ana V.Diez Roux

^*Corresponding author for this work

Preventive Medicine

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Racial disparities in cardiovascular health (CVH) continue to remain a public health concern in the United States. We use unique population-based data from the Multi-Ethnic Study of Atherosclerosis cohort to explore the black-white differences in optimal CVH. Utilizing geographically weighted regression methods, we assess the spatial heterogeneity in black-white differences in optimal CVH and the impact of both individual- and neighborhood-level risk factors. We found evidence of significant spatial heterogeneity in black-white differences that varied within and between the five sites. Initial models showed decreased odds of optimal CVH for blacks that ranged from 60% to 70% reduced odds – with noticeable variation of these decreased odds within each site. Adjusting for risk factors resulted in reductions in the black-white differences in optimal CVH. Further understanding of the reasons for spatial heterogeneities in black-white differences in nationally representative cohorts may provide important clues regarding the drivers of these differences.

Original language	English (US)
Article number	100332
Journal	Spatial and Spatio-temporal Epidemiology
Volume	33
DOIs	https://doi.org/10.1016/j.sste.2020.100332
State	Published - Jun 2020

Funding

Research reported in this publication was supported by the National Heart, Lung, And Blood Institute of the National Institutes of Health under Award Number K01HL133515 . The content is solely the responsibility of the authors and does notnecessarily represent the official views of the National Institutes of Health. This research was supported by contracts 75N92020D00001 , HHSN268201500003I , N01-HC-95159 , 75N92020D00005 , N01-HC-95160 , 75N92020D00002 , N01-HC-95161 , 75N92020D00003 , N01-HC-95162 , 75N92020D00006 , N01-HC-95163 , 75N92020D00004 , N01-HC-95164 , 75N92020D00007 , N01-HC-95165 , N01-HC-95166 , N01-HC-95167 , N01-HC-95168 and N01-HC-95169 from the National Heart, Lung, and Blood Institute , and by grants UL1-TR-000040 , UL1-TR-001079 , and UL1-TR-001420 from the National Center for Advancing Translational Sciences (NCATS). The authors thank the other investigators, the staff, and the participants of the MESA study for their valuable contributions. A full list of participating MESA investigators and institutions can be found at http://www.mesa-nhlbi.org .

Keywords

Cardiovascular health
Disparities
Spatial heterogeneity

ASJC Scopus subject areas

Geography, Planning and Development
Infectious Diseases
Health, Toxicology and Mutagenesis
Epidemiology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Tabb, L. P., McClure, L. A., Ortiz, A., Melly, S., Jones, M. R., Kershaw, K. N., & Roux, A. V. D. (2020). Assessing the spatial heterogeneity in black-white differences in optimal cardiovascular health and the impact of individual- and neighborhood-level risk factors: The Multi-Ethnic Study of Atherosclerosis (MESA). Spatial and Spatio-temporal Epidemiology, 33, Article 100332. https://doi.org/10.1016/j.sste.2020.100332

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title = "Assessing the spatial heterogeneity in black-white differences in optimal cardiovascular health and the impact of individual- and neighborhood-level risk factors: The Multi-Ethnic Study of Atherosclerosis (MESA)",

abstract = "Racial disparities in cardiovascular health (CVH) continue to remain a public health concern in the United States. We use unique population-based data from the Multi-Ethnic Study of Atherosclerosis cohort to explore the black-white differences in optimal CVH. Utilizing geographically weighted regression methods, we assess the spatial heterogeneity in black-white differences in optimal CVH and the impact of both individual- and neighborhood-level risk factors. We found evidence of significant spatial heterogeneity in black-white differences that varied within and between the five sites. Initial models showed decreased odds of optimal CVH for blacks that ranged from 60% to 70% reduced odds – with noticeable variation of these decreased odds within each site. Adjusting for risk factors resulted in reductions in the black-white differences in optimal CVH. Further understanding of the reasons for spatial heterogeneities in black-white differences in nationally representative cohorts may provide important clues regarding the drivers of these differences.",

keywords = "Cardiovascular health, Disparities, Spatial heterogeneity",

author = "Tabb, {Loni Philip} and McClure, {Leslie A.} and Angel Ortiz and Steven Melly and Jones, {Miranda R.} and Kershaw, {Kiarri N.} and Roux, {Ana V.Diez}",

note = "Funding Information: Research reported in this publication was supported by the National Heart, Lung, And Blood Institute of the National Institutes of Health under Award Number K01HL133515 . The content is solely the responsibility of the authors and does notnecessarily represent the official views of the National Institutes of Health. This research was supported by contracts 75N92020D00001 , HHSN268201500003I , N01-HC-95159 , 75N92020D00005 , N01-HC-95160 , 75N92020D00002 , N01-HC-95161 , 75N92020D00003 , N01-HC-95162 , 75N92020D00006 , N01-HC-95163 , 75N92020D00004 , N01-HC-95164 , 75N92020D00007 , N01-HC-95165 , N01-HC-95166 , N01-HC-95167 , N01-HC-95168 and N01-HC-95169 from the National Heart, Lung, and Blood Institute , and by grants UL1-TR-000040 , UL1-TR-001079 , and UL1-TR-001420 from the National Center for Advancing Translational Sciences (NCATS). The authors thank the other investigators, the staff, and the participants of the MESA study for their valuable contributions. A full list of participating MESA investigators and institutions can be found at http://www.mesa-nhlbi.org . Publisher Copyright: {\textcopyright} 2020",

year = "2020",

month = jun,

doi = "10.1016/j.sste.2020.100332",

language = "English (US)",

volume = "33",

journal = "Spatial and Spatio-temporal Epidemiology",

issn = "1877-5845",

publisher = "Elsevier Ltd",

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Tabb, LP, McClure, LA, Ortiz, A, Melly, S, Jones, MR, Kershaw, KN & Roux, AVD 2020, 'Assessing the spatial heterogeneity in black-white differences in optimal cardiovascular health and the impact of individual- and neighborhood-level risk factors: The Multi-Ethnic Study of Atherosclerosis (MESA)', Spatial and Spatio-temporal Epidemiology, vol. 33, 100332. https://doi.org/10.1016/j.sste.2020.100332

Assessing the spatial heterogeneity in black-white differences in optimal cardiovascular health and the impact of individual- and neighborhood-level risk factors: The Multi-Ethnic Study of Atherosclerosis (MESA). / Tabb, Loni Philip; McClure, Leslie A.; Ortiz, Angel et al.
In: Spatial and Spatio-temporal Epidemiology, Vol. 33, 100332, 06.2020.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Assessing the spatial heterogeneity in black-white differences in optimal cardiovascular health and the impact of individual- and neighborhood-level risk factors

T2 - The Multi-Ethnic Study of Atherosclerosis (MESA)

AU - Tabb, Loni Philip

AU - McClure, Leslie A.

AU - Ortiz, Angel

AU - Melly, Steven

AU - Jones, Miranda R.

AU - Kershaw, Kiarri N.

AU - Roux, Ana V.Diez

N1 - Funding Information: Research reported in this publication was supported by the National Heart, Lung, And Blood Institute of the National Institutes of Health under Award Number K01HL133515 . The content is solely the responsibility of the authors and does notnecessarily represent the official views of the National Institutes of Health. This research was supported by contracts 75N92020D00001 , HHSN268201500003I , N01-HC-95159 , 75N92020D00005 , N01-HC-95160 , 75N92020D00002 , N01-HC-95161 , 75N92020D00003 , N01-HC-95162 , 75N92020D00006 , N01-HC-95163 , 75N92020D00004 , N01-HC-95164 , 75N92020D00007 , N01-HC-95165 , N01-HC-95166 , N01-HC-95167 , N01-HC-95168 and N01-HC-95169 from the National Heart, Lung, and Blood Institute , and by grants UL1-TR-000040 , UL1-TR-001079 , and UL1-TR-001420 from the National Center for Advancing Translational Sciences (NCATS). The authors thank the other investigators, the staff, and the participants of the MESA study for their valuable contributions. A full list of participating MESA investigators and institutions can be found at http://www.mesa-nhlbi.org . Publisher Copyright: © 2020

PY - 2020/6

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N2 - Racial disparities in cardiovascular health (CVH) continue to remain a public health concern in the United States. We use unique population-based data from the Multi-Ethnic Study of Atherosclerosis cohort to explore the black-white differences in optimal CVH. Utilizing geographically weighted regression methods, we assess the spatial heterogeneity in black-white differences in optimal CVH and the impact of both individual- and neighborhood-level risk factors. We found evidence of significant spatial heterogeneity in black-white differences that varied within and between the five sites. Initial models showed decreased odds of optimal CVH for blacks that ranged from 60% to 70% reduced odds – with noticeable variation of these decreased odds within each site. Adjusting for risk factors resulted in reductions in the black-white differences in optimal CVH. Further understanding of the reasons for spatial heterogeneities in black-white differences in nationally representative cohorts may provide important clues regarding the drivers of these differences.

AB - Racial disparities in cardiovascular health (CVH) continue to remain a public health concern in the United States. We use unique population-based data from the Multi-Ethnic Study of Atherosclerosis cohort to explore the black-white differences in optimal CVH. Utilizing geographically weighted regression methods, we assess the spatial heterogeneity in black-white differences in optimal CVH and the impact of both individual- and neighborhood-level risk factors. We found evidence of significant spatial heterogeneity in black-white differences that varied within and between the five sites. Initial models showed decreased odds of optimal CVH for blacks that ranged from 60% to 70% reduced odds – with noticeable variation of these decreased odds within each site. Adjusting for risk factors resulted in reductions in the black-white differences in optimal CVH. Further understanding of the reasons for spatial heterogeneities in black-white differences in nationally representative cohorts may provide important clues regarding the drivers of these differences.

KW - Cardiovascular health

KW - Disparities

KW - Spatial heterogeneity

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DO - 10.1016/j.sste.2020.100332

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SN - 1877-5845

VL - 33

JO - Spatial and Spatio-temporal Epidemiology

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ER -

Tabb LP, McClure LA, Ortiz A, Melly S, Jones MR, Kershaw KN et al. Assessing the spatial heterogeneity in black-white differences in optimal cardiovascular health and the impact of individual- and neighborhood-level risk factors: The Multi-Ethnic Study of Atherosclerosis (MESA). Spatial and Spatio-temporal Epidemiology. 2020 Jun;33:100332. doi: 10.1016/j.sste.2020.100332

Assessing the spatial heterogeneity in black-white differences in optimal cardiovascular health and the impact of individual- and neighborhood-level risk factors: The Multi-Ethnic Study of Atherosclerosis (MESA)

Abstract

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

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