Assessment and Key Targets for Therapy in the Post-Myocardial Infarction Patient with Left Ventricular Dysfunction

James D. Flaherty*, James E. Udelson, Mihai Gheorghiade, Edwin Wu, Charles J. Davidson

*Corresponding author for this work

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

In the post-myocardial infarction (MI) patient with coronary artery disease (CAD) and left ventricular dysfunction (LVD), ischemia and adverse remodeling hinder myocardial performance and increase electrical instability. Collectively, the coronary arteries, myocardium, and conduction system represent the principal pathophysiologic targets in MI complicated by LVD. Consequently, an accurate assessment of disease severity in these targets is essential for the design of an effective therapeutic program. This review describes the current modalities for assessing the key pathophysiologic targets in post-MI patients with LVD and the effects of systemic factors on cardiac disease severity.

Original languageEnglish (US)
Pages (from-to)5G-12G
JournalAmerican Journal of Cardiology
Volume102
Issue number5 SUPPL.
DOIs
Publication statusPublished - Sep 8 2008

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ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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