Assessment of flow instabilities in the healthy aorta using flow-sensitive MRI

Aurélien F. Stalder, Alex Frydrychowicz, Max F. Russe, Jan G. Korvink, Jürgen Hennig, Kuncheng Li*, Michael Markl

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

47 Scopus citations

Abstract

Purpose: To assess blood flow velocities and spatial distribution of aortic Reynolds numbers in vivo using flow-sensitive magnetic resonance imaging (MRI) and probe for flow instabilities along the aorta based on an empirical model for physiological pulsatile blood flow. Materials and Methods: Thirty young healthy volunteers were examined by flow-sensitive MRI at eight imaging planes distributed along the thoracic aorta. Flow, Womersley, Strouhal, Reynolds, and critical Reynolds numbers were calculated and used to assess the presence of flow instabilities. Results: The average peak Reynolds number was higher in the ascending (≈4500) and descending aorta (≈4200) than in the aortic arch (≈3400). According to the calculated critical Reynolds numbers, flow instabilities were prominent in the ascending (14/30 volunteers) and descending aorta (22/30 volunteers) but not in the aortic arch (3/30 volunteers). A significant difference (P < 0.05) in supracritical peak Reynolds numbers was observed between genders. The supracritical Reynolds number, indicating flow instabilities, significantly correlated (P < 0.05) with body weight (r = 0.34), aortic diameter (r = 0.48), and cardiac output (r = 0.53). Conclusion: Flow-sensitive MRI was used to indirectly assess the presence of flow instabilities in vivo. The results in volunteers indicate the presence of flow instabilities in the young healthy aorta with a higher prevalence for men than women.

Original languageEnglish (US)
Pages (from-to)839-846
Number of pages8
JournalJournal of Magnetic Resonance Imaging
Volume33
Issue number4
DOIs
StatePublished - Apr 2011

Keywords

  • Aorta
  • Phase-contrast MRI
  • Reynolds number
  • Strouhal number
  • Turbulence
  • Womersley number

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Assessment of flow instabilities in the healthy aorta using flow-sensitive MRI'. Together they form a unique fingerprint.

Cite this